Distinguishing monozygotic (MZ; identical) from dizygotic (DZ; non-identical) twins is important to parents of twins. It is often the first question that parents of twins are asked by family and friends. Parents also use knowledge about their twins' zygosity to understand similarities and ...
Heritability estimates are often calculated from twin data by doubling the reared-together MZ (monozygotic, identical) versus DZ (dizygotic, fraternal) correlation or concordance rate10difference, or by claiming that the reared-apart MZ twin pair correlation “directly estimates” heritability (reared-ap...
Joseph K, Liu S, Demissie K, Wen SW, Platt RW, Ananth CV, Dzakpasu S, Sauve R, Allen AC, Kramer MS, The Fetal and Infant Health Study Group of the Canadian Perinatal Surveillance System 2003 A parsimonious explanation for intersecting perinatal mortality curves: understanding the effect of...
We performed a classical twin study of HbA(1c) in healthy nondiabetic female twins and 42 monozygotic (MZ) and 47 dizygotic (DZ) pairs. Interclass correlations (r) were higher in MZ (r = 0.77) compared with DZ (r = 0.53) twin pairs, suggesting a substantial genetic effect; this was...
Twin-based heritability estimates compare correlations within monozygotic and dizygotic twins and can be calculated as h2=(rMZ-rDZ), where r is the correlation in DNA methylation levels at a particular locus in each pair type (monozygotic (MZ) or dizygotic (DZ)). The classical twin study ...
Identical twins [MZ] share 100% of their genetic material, whereas non-identical [DZ] twins share approximately 50% of their segregating genes. However, both types of twins share their environments to a very similar extent (e.g. gestated in the same mother, born at the same time, raised...
This process, known as “epigenetic drift”, also occurs in individuals with identical genetic backgrounds such as monozygotic twins (Fraga et al., 2005). On the other hand, some locus-specific DNA methylation changes are highly reproducible across aged people, independently of gender and tissue ...
Humans are diploid, meaning they have two copies of each of the 23 different types of chromosomes found in humankind. This means that each human has 46 chromosomes in total, half of which come from each of their parents. Some people can have more or less chromosomes. For example...
We further examined the model performance of identifying twin versus non-twin individuals using the EEG data during the eye-closed resting task. To allow for a fair performance comparison between models that distinguished twins versus non-twins, we equalized the number of individuals to be identified...
a. The correlations between MZ twins and the correlations between DZ twins were similar. b. The correlations between DZ twins were about the same as those be Kia is a foster child in an American home. Based on th...