The perfect example of diastereomers is when we look at the cis and trans isomer structure. Diastereomers, unlike enantiomers, are not mirror images of each other. However, they are still non-superimposable. Enantiomers and diastereomers are both types of stereoisomers and optical isomers, and ...
Cis and trans stilbene can be distinguished from the difference in IR absorption. Two enantiomers can be distinguished from their different NMR spectra. Diastereomers cannot be distinguished by NMR spectra. (A)True True False False (B)False True...
The corrected mean absolute error (CMAE), the average of the differences between the computed and experimental chemical shifts for each of the 11 lactones, is encouragingly small (0.02-0.08 ppm for 鹿H or 0.8-2.2 ppm for 13C). Three pairs of cis versus trans diastereomeric lactones were ...
A comprehensive Kinetic Analysis of the Interconversion of cis- and trans-4-Hydroxycyclophosphamide with Aldophosphamide and the Concomitant Partitioning of Aldophosphamide between Irreversible Fragmentation and Reversible Conjugation Pathways” Journal of Medicinal Chemistry, 1984, pp. 466-485, vol. 27, ...
Under physiologically relevant conditions, cis-bis(2,2'-bipyridine)- dichlororuthenium(II), [cis-Ru(2,2'-bipy)_2Cl_2] was observed to bind to folic acid via replacement of the two chloride ligands. This binding was shown to be pH dependent and afforded diastereomers, the structures of ...
) or -N(R10)R11); R6, R7 = H (cis configuration); R8, R9 = H (cis or trans); Z = O, S or H2; R10, R11 = H, 1-6C alkyl or 1-6C alkoxy.THAL CLAUDEPUJOL JEAN-FRANCOISPOTIER PIERRE
tandem lesion appears in single or double-stranded oligonucleotides next to dU, on its 3′-end side. The cdA shift to the 5′-end side of dU inss-DNA stops this effect in both cdA diastereomers. Surprisingly, in the case ofds-DNA, 5′S-cdA completely blocks uracil excision by UDG. ...