But what are the world's rarest diseases? It can be a tricky question to answer. Would we necessarily know about them, since they occur so infrequently? New diseases often pop up when another organism's viruses or bacteria adapt to human hosts. Theoretically, new genetic anomalies could also...
These lakes share the characteristics of high altitude locations (above 1200 meters), subtropical plateau monsoon climate, an average annual rainfall of ~1000 mm, low temperature, and high vulnerability to human disturbance28,31. Water samples were collected from each lake between August and ...
Additionally, using the CellSens software, the mean gray value was determined for 30 representative cells (B). A representative result of three independent experiments is presented. In order to assess the significance between the samples, an ANOVA with Dunnett’s multiple comparisons post-hoc test ...
Although gradually declining in incidence, gastric cancer has remained a substantial disease burden and an epidemiological challenge worldwide. In this review article, we provide an update on existing screening programs in high-risk countries and put forth considerations for potentially applicable gastric ...
Currently, fungi-based engineered living materials require either a heat-killing step to eliminate the living cells or the use of co-culture with a model organism for functional enhancement, which diminishes the ease of engineering and diversity of these materials. By employing a simple filtration ...
Aging is a universal, multifactorial and progressive process determined by an intrinsic decreased ability of the organism to counterbalance the adverse effects of accumulating extrinsic risk factors. It manifests as functional impairment of cells, tissues and organs and augments the susceptibility to chron...
An integration in the totality of a complex cell system or an organism would require a completely different experimental setup. Therefore, our model system is limited to the identification of fundamental principles of gravity–structural–functional relations. According to the self-organized criticality ...
For other structures of an organism, stability can be important and advantageous at all stages of ontogenesis, and therefore selection can favor Alu deletions. By affecting gene activity, Alu deletions and Alu insertions together can modulate the effects that influence the development of a highly ...
s structure [47,48]. In this respect, it is essential to highlight that the parotid gland possesses peroxisomal enzymes and several other antioxidative catalysts that detoxify H2O2produced by peroxisomal oxidases [28]. The striated duct cells within the human parotid gland possess an excessive ...
Cell cycle progression is an essential mechanism that ensures DNA replication, cell growth and division, and organism renewal. However, the overexpression of growth factors or mutations in genes/lack of controlling tumor suppressor proteins leads to the inability of cells to exit the cell cycle and...