T. (2004). Surfing, regulating and capturing: are all microtubule- tip-tracking proteins created equal? Trends Cell Biol. 14, 491- 496.Vaughan, K. T. (2004). Surfing, regulating and capturing: are all microtubule-tip- tracking proteins created equal? Trends Cell Biol. 14, 491-496....
Post-translational protein translocation: not all hsc70s are created equal Major histocompatibility (MHC) class I glycoproteins are specialized to present to CD8+ T cells, peptides that originate from proteins synthesized within t... JL Brodsky 被引量: 0发表: 1996年 ...
Intrinsically disordered proteins and protein regions (IDPs) are prevalent in all proteomes and are essential to cellular function. Unlike folded proteins, IDPs exist in an ensemble of dissimilar conformations. Despite this structural plasticity, intramo
The article reports on the result of Jennifer Lippincott-Schwartz and her colleagues' research on the main models for intra-Golgi transport of cargo proteins. They presented a new model, which involves rapid division of Golgi enzymes and transmembrane cargo between two lipid phases along with a ...
A.L.G. participated in many of the studies, identifying anomalies in PLD4- and PLD3-deficient mice and their myeloid cell cytokine responses and in the preparation of PLD3 and PLD4 proteins; D.H. elucidated the enzymatic function of PLD3 and PLD4, carried out all studies in 293 cells,...
Thus, we tested the performance of these methods on the same set of 92 fold switchers, generating >280,000 predictions in all. Upon assessing these predictions, we found that all AF2-based methods and AF3 predict fold-switching proteins likely in its training set with modest success (32/92...
The total numbers of genes were 4,193, which covered 88.6% of the genome and encoded 3,176 proteins. COG function classification revealed that strain 50-1 has roles in amino acid transport and metabolism; carbohydrate transport and mechanism; and secondary metabolite biosynthesis, transport, and ...
We find 8 pairs where both proteins had no detected abundance across all 23 tissues. There were 133 pairs where one protein of a pair had detectable abundance and the other did not. A set of 353 (10%) of the pairs exhibited alternating dominance, where both proteins had at least 1 ...
Therefore, the mechanisms of amyloid formation are of central interest for a better understanding of this class of shape-shifting proteins. Although tremendous progress has been made in the understanding of the structural transition of a number of amyloid proteins, detailed molecular insights into the...
whereas the 40 and 50% consisted mainly of larger species. The size of the fractionated proteins increases as a function of sucrose gradient as confirmed independently by single-molecule fluorescence and AFM. It must be noted that these techniques are complementary and should not be expected to re...