Dennis Crompton, an influential figure in the field of architecture,passed awayon January 21, 2025, at the age of 90. Born in Blackpool in 1935, Crompton's remarkable career spanned several decades and left an indelible mark on modern architecture. As a key member of theavant-garde architec...
Figure 2 Proteomic characterization of the APE1 interactome. (A) Representative Western blotting to confirm APE1 pulldown in the co-immunoprecipitation experiment. Western blotting analysis was performed on total HeLa cell clone extracts (INPUT) and on co-immunoprecipitated material (IP) with specific...
The genetic architecture of the human thalamus and its overlap with ten common brain disorders Article Open access 18 May 2021 Introduction The brainstem is a critical regulator of vital bodily functions and includes the midbrain, pons, and the medulla oblongata1,2. These regions subserve emotion...
Influential figureDeborah Berke, FAIA, LEED AP,has been announcedas the recipient of the2025 AIA Gold Medal, in recognition of her four-decade career integrating design prowess, and academic leadership demonstrating social and environmental responsibility. Her work, encompassing residential, institutional,...
Download: Download full-size image Figure S2. Negative-Stain EM of Yeast UTP-A and UTP-B Modules, 5′-ETS Recycling Intermediate, and the 90S Pre-ribosome, Related to Figure 1 (A) Negative-stain electron microscopy (ns-EM) of affinity-purified yeast UTP-A (via Utp10-FTpA), UTP-B (...
which further promotes diminished loading. Here we represent both loss of inhibition and loss of connection, and propose that debate and discussion is warranted on the influence that each of these has on the clinical manifestation of CP. Figure our own, created using Adobe Illustrator (Adobe, Inc...
Figure 8 Surface Plasmon Resonance analysis of CBEL-glycoproteins interactions. Human lactotransferin (LTF) or melon hydroxyprolin-rich glycoprotein (HRGP) were passed over the CBEL chip surface at concentrations of 25 or 100 μg/ml respectively. Then, either HBS-Ep buffer alone (control) or ...
Figure 3. Genetic Correlations for Clinical and Symptom-Based Depression With Cardiometabolic and Mental Health Traits View LargeDownload Correlations are shown for samples with East Asian ancestry (A) and European ancestry (B) for the depression studies. For the cardiometabolic and mental health trai...
(e.g., anemia), as well as biomarkers from various human organs (e.g., liver) (Fig.2B). We then performed positional and functional annotations to map SNPs to genes associated with GM, WM, and FC-BAG loci (Method 4C). Figure2C-Eshowcased the regional Manhattan plot of one genomic ...
Fig. 1 Study design and work flow. The figure illustrates the study design and key findings of the study Full size image Results Heritability of lipid species First, we determined SNP-based heritability for each of the lipid species and traditional lipids using genetic relationship matrix for all...