在体内___发挥抗癌作用。Ara-CTP通过抑制DNA多聚酶及少量掺入DNA,阻止DNA的合成,抑制细胞的生长。 ②吉西他滨是一个前药,是细胞内脱氧胸苷激酶磷酸化的底物 2、抗嘌呤代谢类抗肿瘤药物(本类药物主要是次黄嘌呤与鸟嘌呤的衍生物) 6-巯基嘌呤 抗痛风药别嘌呤醇可增强本品的抗肿瘤作用及毒性,合用时应注意减量...
常用中文名:Ara-CTP 常用英文名:Cytarabine triphosphate 分子式:C10H18N3O13P3 分子量:481.18400 密度:2.5g/cm3 沸点:849.2ºC at 760mmHg 熔点:N/A 闪点:467.4ºC 储存条件:2-8°C,密封,干燥 供应商信息 上海阿拉丁生化科技股份有限公司 ...
Cytarabine triphosphate(Synonyms: Ara-CTP) Cytarabine triphosphate (Ara-CTP),一种 Cytarabine 的活性代谢物,是 DNA 合成的竞争性抑制剂。细胞内 Cytarabine triphosphate 水平可用于预测白血病母细胞对 Cytarabine 的化学敏感性。 Cytarabine triphosphateChemical Structure CAS No. :13191-15-6 *Please selectQuantityb...
英文名称:Ara-cytidine-5'-triphosphate (ara-CTP), S pack总访问:266 国产/进口:进口半年访问:22 产地/品牌:德国Jena产品类别:生化试剂 规格:NU-1170S最后更新:2024-12-5 货号: CAS 号: 参考报价:3754 立即询价电话咨询 [发表评论][本类其他产品][本类其他供应商][收藏] ...
英文名称:ara-Cytidine-5'-triphosphate (ara-CTP), S pack 欣博盛生物科技有限公司 联系电话:4006-800-892 电子邮件:info@neobioscience.com CB指数:58 网址:www.nbs-bio.com 相关信息:产品目录(6207) 用户评价 英文名称:ara-Cytidine-5'-triphosphate (ara-CTP), S pack Tag...
We describe here the effects of ara-CTP, which is the most prominent form of ara-C in the cell, onreplicative systemsofand on isolated DNA polymerases II and III.G. V. RAMA REDDYM. GOULIANS. S. HENDLERNature New Biology
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阿 糖胞苷(Ara-C)药理作用首先是在代谢酶的作用下转化成三磷酸阿糖胞苷(Ara-CTP),而人体内同时存在使得Ara-CTP分解的酶.为了明确代 谢酶在AML耐药中所起的作用,我们特... 万海霞,陈芳源,王海嵘,... - 《中华血液学杂志》 被引量: 11发表: 2005年 阿糖胞苷代谢关键酶蛋白活性,基因表达与不同类型儿童急性...
Using the genotypes of SNPs associated with intracellular ara-CTP levels we created a risk score by combining the effect of SNPs reported in each patient. For this we took into consideration the direction of genotype association for each SNP. For example, if the SNP is associated with higher ...
The mechanism of this combination effect not well elucidated but the intracellular uptake of ara-C was higher when cells were pre-exposed to MTX. In this experiment, the intracellular ara-CTP was measured by HPLC after MTX and ara-C were sequentially administered to BDF1 mice bearing L1210 ...