First of all I want to make it clear that I have been a big fan of properly conducted replication and validation studies for many years – long before the current hype of what one might call a shallow replication research program. Please note also that one of my own studies has been incl...
We did not have research funding for this study, there was no control group, and many variables. Our sample, as typical in MS, often had to cancel appointments due to health problems, transport or general difficulties, but still achieved a remarkable result. It was interesting to note that ...
ISS data and microarray data were log2-transformed and correlations between the data sets were tested using Pearson's correlation. In order to enable log2-transformation of the dataset in the presence of zero values for certain genes, “1” was added as a constant to all values of the data...
Supports worldwide range input power line voltages Input power factor control (PFC) function for 90 V AC to 250 V AC helps minimize input power line current. 1.3 Applications Research, development, and testing of various small-capacity built-in power source units Research, ...
[3]. These effects vary within the group of PFAS, with most compounds not yet been investigated, as research has primarily focused on a few compounds [4]. This includes, for example, perfluorooctanoic acid (PFOA), which is classified as a persistent compound within the subgroup of ...
An experimental prototype version of the Spotlight SAR, which is the highest resolution SAR system in Canada, is flown on a Convair 580 aircraft operated by the National Research Council's Institute for Aerospace Research. The radar was recently used in an experiment in which an ocean-going ...
A suitable computer program for carrying out such an alignment is the GCG Wisconsin Bestfit package (Devereux et al 1984 Nuc. Acids Research 12 p 387). Examples of other software than can perform sequence comparisons include, but are not limited to, the BLAST package (see Ausubel et al., ...
Rubin, et al., “Optimization of Electric Field Parameters for the Control of Bone Remodeling: Exploitation of an Indigenous Mechanism for the Prevention of Osteopenia”, Journal of Bone and Mineral Research, vol. 8, Supplement 2, 1993, pp. S573-S581. ...
. Most of these pathological conditions are associated with aging. For example, impairment of Nitric Oxide signalling has been reported in coronary spastic angina (Miyamoto Yet al. Hum Mol Genet. 2000 Nov. 1; 9(18): pages 2629-37), thrombosis (Loscalzo J, Circulation Research. 2001; 88, ...
13. A method for preparing a derivative of IL-22, comprising covalently attaching a fatty acid to an 1L-22 protein, wherein: (i) the IL-22 protein is native mature human IL-22 (hIL-22; SEQ ID NO. 1) or a variant thereof, wherein the variant (a) comprises a variation within SEQ...