A. Zika viral polymerase inhibition using anti-HCV drugs both in market and under clinical trials. J Med Virol 88, 2044–2051 (2016). 15. Xu, M. et al. Identification of small-molecule inhibitors of Zika virus infection and induced neural cell death via a drug repurposing screen. Nat ...
Until now, stem cell therapy has mainly been used in unregulated private clinics or as an experimental treatment in clinical trials (see “The dangerous allure of stem cells“). A handful of treatments have been approved, but these in...
Clinical Trials: Part 1. How prescription drugs are developed, tested, and approved.(THE MEDICAL DIGITAL)[ILLUSTRATION OMITTED] In my last column ("How Safe Are the Prescription Drugs We Take?"...Ardito, Stephanie C
The study was designed, implemented and reported in accordance with Good Clinical Practice, local regulations, and the ethical principles of the Declaration of Helsinki. This study is registered on clinicaltrials.gov (NCT00546143). 2.2. Treatment Patients were randomised to one of three omalizumab do...
The recombinant human monoclonal antibody against SARS-CoV-2 for injection, named F61 and designated for early treatment of novel coronavirus infection, has been approved by the National Medical Products Administration for clinical trials, said Zhu Jingjin, Party secretary of CNBG, at the China Inter...
Overall, 4471 patients from 6 randomized controlled trials (RCTs), with 2190 patients in the treatment group and 2281 patients in the placebo group meeting the inclusion criteria. FDA-approved anti-Aβ mabs showed statistically significant improvements in clinical outcomes, including CDR-SB (P =...
DapaCare is a robust programme of clinical trials to evaluate the potential CV, renal and organ protection benefits of Farxiga. It includes more than 35 completed and ongoing Phase IIb/III trials in more than 35,000 patients, as well as more than 2.5 million patient-years’ e...
BEIJING, Aug. 15 (Xinhua) -- A new injection, which is an mRNA vaccine for Epstein-Barr virus positive tumors, has been approved by the Center for Drug Evaluation of the National Medical Products Administration for Phase-I clinical trials. ...
et al. Combinations of beta-Lactam Antibiotics Currently in Clinical Trials Are Efficacious in a DHP-I-Deficient Mouse Model of Tuberculosis Infection. Antimicrob Agents Chemother 59, 4997–4999 (2015). Article CAS PubMed PubMed Central Google Scholar Barriere, S. L. & Flaherty, J. F. ...
The Digene Hybrid Capture 2 (HC2) HPV DNA Test (Qiagen, Gaithersburg, MD) has been the most widely used molecular HPV assay in most clinical trials and has been extensively reviewed.11 This assay is FDA approved for triage in cases of equivocal cytology results in the presence of atypical ...