Background: despite vigorous efforts at curbing tobacco consumption and aggressive combined modality treatment programmes, both incidence and mortality from lung cancer have remained virtually unchanged in the last 10 years and there is a clear need for more effective innovative therapies. The direct ...
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Interdisciplinary Forum: From Genetic Diagnosis to Gene Therapy in Oncology The experimental approaches attempted to date, reviewed herein, indicate overall that anti-angiogenic gene therapy hasefficacy mainly as an early intervention ... Kurt S. ZänkerHans P. Huber - 《Journal of Cancer Research&...
In addition, some types of gene therapies have been shown to enhance the effects of chemotherapy and other biotherapies such that they might serve as adjunct treatment in diseases for which no one therapy is curative. Clinical trials employing gene transfer for the treatment of cancer have been ...
Candidate genes for gene therapy are those encoding for neurotrophins and neurotransmitters for symptomatic therapy and, in the case of neurodegenerative disorders with localized gene defects, the wild-type allele as a causal treatment approach. In this review article, we describe some of the most ...
Nature 506, 376–381 (2014).” All subsequent references (5–161) should be renumbered accordingly (6–162) in the list and text. Also, several of the gene symbols in Table 2 were formatted incorrectly (without commas); the correct gene symbols are as follows: column 3 row 13, RBM17...
Gene Therapy volume 28, pages 290–305 (2021)Cite this article 32k Accesses 51 Altmetric Metrics details Abstract The novel coronavirus pneumonia (COVID-19) is a highly infectious acute respiratory disease caused by Severe Acute Respiratory Syndrome-Related Coronavirus (SARS-CoV-2) (Prec Clin Med...
Hair cells in mammal... BW Kesser,AK Lalwani - Advances in oto-rhino-laryngology 被引量: 80发表: 2009年 Gene therapy for the inner ear Animal studies on inner ear development, repair and regeneration provide understanding of molecular pathways that can be harnessed for treating inner ear d....
The use of intravenous immunoglobulin (IVIG), rituximab, biologic agents including tumor necrosis factor (TNF) inhibitors, stem-cell transplantation, gene therapy, and vascular occlusion resistance training are reviewed here. As our understanding of disease pathogenesis at the immunologic, genetic, and ...
The physiology, including the reproductive physiology, of an animal can be monitored largely not only by measuring key hormones but also by examining the expression of individual genes or a set of genes. Traditionally, this has been achieved in what is known as the “candidate gene approach”....