Application of protein engineering on alpha-L-arabinofuranosidase (abfa) from Thermophilic BacteriumThe aim of this study is to improve the catalytic activity of thermostable abfA enzyme in several conditions such as various organic solvent, temperature and pH by directed evolution for the first time...
Application of protein engineering on α-l-arabinofuranosidase (abfa) from Thermophilic BacteriumApplication of protein engineering on α-l-arabinofuranosidase (abfa) from Thermophilic Bacteriumdoi:10.1016/j.copbio.2011.05.262YusufSürmeliHüseyinIl
New food raw materials refer to items that posses the characteristics of food ingredients, meet the necessary nutritional requirements, are non-toxic and harmless, do not cause any acute, subacute, chronic, or other potential harm to human health, and are not part of the traditional dietary habi...
naturally occurring ribozymes have been extensively investigated concerning their structure and functional mechanisms. On the other hand, the knowledge gained from these studies has been used to engineer ribozyme variants with novel properties. In addition to RNA engineering by means of rational...
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Recently, a magnetic protein was discovered, and a multimeric magnetosensing complex was validated, which may form the basis of magnetoreception. In this study, the magnetic protein was firstly used in biotechnology application, and a novel convenient one-step purification and immobilization method wa...
Protein thermostability has been investigated by two approaches. (A) Computational. To study the relationship between thermostability and conformational characteristics of proteins, 195 single amino acid residue replacements have been analysed for several protein conformational characteristics. From the analyses...
of bio-engineering in improving geotechnical and geoenvironmental properties of soils along with their working mechanisms in labs and field. Moreover, the effect of bio-engineering as a remediation measure to soil contamination has also been addressed. This review article also highlights the potential ...
Figure 4 Development of bone substitute materials based on osteoimmunomodulation 图4 基于骨免疫微环境调控的骨替代材料研发理念基于骨免疫微环境调控的研发理念强调通过改变植入材料的理化性能,如化学构成、表面性质及机械性能等,进而调控免疫细胞,营造利于成骨的免疫微环境,从而促进间充质干细胞成骨方向的分化,提高骨...
et al. Improving the DNA specificity and applicability of base editing through protein engineering and protein delivery. Nat. Commun. 8, 15790 (2017). Article CAS PubMed PubMed Central Google Scholar Wang, X. et al. Efficient base editing in methylated regions with a human APOBEC3A–Cas9 ...