Mass spectrometry (MS) has been accepted as a powerful technology to study epigenetic mechanisms, understanding the importance of the combinatorial histone codes on the determination of cell phenotypes and in the etiology of diseases. In this chapter, we introduce the principles of mass spectrometry....
In the last few decades, research reports suggested that characterize proteins could be desorbed directly from PPNs using matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF-MS), and the use of MS to investigate PPN, PPN proteins, and the PPN proteome has ...
Welsh School of Pharmacy, University of Wales Institute of Science and Technology, Cathays Park, Cardiff, U.K.H. J. SmithWelsh School of Pharmacy, University of Wales Institute of Science and Technology, Cathays Park, Cardiff, U.K.John Wiley & Sons, LtdJournal of Pharmacy & Pharmacology...
Mass spectrometry imaging is a frontier technique which connects classical mass spectrometry with ion imaging. Various types of chemicals could be visualized in their native tissues using mass spectrometry imaging. Up to now, the most commonly applied mass spectrometry imaging techniques are matrix assist...
Application of mass spectrometry to the measurement of dissolved gases and volatile substances in fermentation. European J. Appl Microbiol. 1, 323–325 (1975). https://doi.org/10.1007/BF01382691 Download citation Received19 February 1975 Issue DateDecember 1975 DOIhttps://doi.org/10.1007/BF01...
Here, an application of bottom-up mass spectrometry (MS) is developed to provide such convenient screening. MS-based techniques have already been applied to characterize residuals in plasma-derived products, such as human serum albumin (HSA) preparations, clotting factor VIII or IX and prothrombin ...
基质辅助激光解吸电离质谱技术(matrixassistedaserdesorption/ionizationmassspectrometry,MAL- DI-MS)和电喷雾电离质谱技术(eectrosprayionizationmassspectrometry,ESI-MS)是产生于20世纪 80年代末期的两项软电离技术 [1,2] ,它们的出现使传统的主要用于小分子物质研究的质谱技术发生了 革命性的变革。这两项技术具有高质...
Mass spectrometry has been used to successfully assay metabolites of SIRT1 activator drugs in plasma and urine12, but to date has not been used to quantify protein levels directly. Mass spectrometry has a great advantage over the conventionally used antibody based methods, such as western blotting...
Mass spectrometry imaging for micro-invasive breast cancerin situby AFAI-MSI New diagnostic markers for micro-invasive breast carcinoma could have a major impact on clinical surgical removal. Determining the presence of micro-invasive cancer can be extremely difficult, particularly in high-grade ductal...
mass spectra (organic substances)analytical methodsChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option....