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INHIBITION OF APP/ABETA/CTF BY TRANSLATIONAL INHIBITION OF APP MRNA RESTORES VESICLE TRANSPORT IN TS65DNdoi:10.1016/j.jalz.2017.07.380MaccecchiniMaria L.Alzheimers & Dementia
Here we shed new light on pathogenic mechanisms by which MT5-MMP controls APP processing and the fate of amyloid beta peptide (Aβ) and its precursor C99. We found that MT5-MMP in HEK carrying the APP Swedish familial mutation (HEKswe) processed APP to release a soluble form of 95 kDa ...
( 2009 ) The GxxxG motif in the transmembrane domain of AbetaPP plays an essential role in the interaction of CTFbeta with the gamma-secretase complex... Guozhang,Mao,Jianxin,... - 《Journal of Alzheimers Disease》 被引量: 9发表: 2009年 The GxxxG Motif in the Transmembrane Domain of ...
英文名称: APP, phosphorylated (T743) (Amyloid Precursor Protein, AAA, AD1, PN2, ABPP, APPI, CVAP, ABETA, PN-II, CTFgamma) (FITC) 英文同义词: APP, phosphorylated (T743) (Amyloid Precursor Protein, AAA, AD1, PN2, ABPP, APPI, CVAP, ABETA, PN-II, CTFgamma) (FITC) CAS号: ...