Significantly decreased concentrations of APO-A1 in dogs with leishmaniosis and a significant increase after a good response to the treatment were observed, suggesting that APO-A1 could be a potential biomarker of treatment monitoring with the advantages of an automated measurement....
Using apolipoprotein A1 (Apo A1), a truncated form of transthyretin, ("transthyretin Delta N10) and/or a cleavage fragment of inter- alpha -trypsin inhibitor heavy chain H4 (IAIH4 fragment) as diagnostic/prognostic indicators of cell proliferative disorder ...
apoE3 is effective at binding the microtubule-binding repeat region of tau, the region responsible for the formation of paired helical filaments; apoE4 does not bind this region and thus may not be as effective at limiting formation of neurofibrillary tangles [25]....
WL also led to significant increases in ApoA1-associated proteins: ANGT; ApoA4; ApoD; ApoM; LpPLA2; PLTP; PON1; and PON3. In conclusion, IR correlates with an atherogenic ApoA1-associated proteome. Both PIO and WL improve IR and the composition of the ApoA1-associated proteome, but PIO...
Exchangeable Apos such as Apo A, Apo C and Apo E must be water-soluble to be exchanged between lipoproteins, while Apo B, as a non-exchangeable apolipoprotein, is highly insoluble in an aqueous medium without interchangeable features with other lipoproteins particles29,30. Non-exchangeable Apo B...
detail and even discussed its effect on metastasis of this tumor. For example, the variations of the apoA-I gene (A1-75 G/A and + 83 C/T) distinguish individuals with a higher risk of developing BC, indicating that lower apoA-I expression is associated with higher BC risk [63]. ...
Angiopoietin-like protein 3 (ANGPTL3) and apolipoprotein C-III (Apo C-III) have been identified as novel lipid-lowering targets. Recent Findings Apo C-III and ANGPTL3 have emerged as novel regulators of triglyceride (TG) and low-density lipoprotein-cholesterol (LDL-C) levels. ANGPTL3 is an...
Using apolipoprotein A1 (Apo A1), a truncated form of transthyretin, ("transthyretin Delta N10) and/or a cleavage fragment of inter- alpha -trypsin inhibitor heavy chain H4 (IAIH4 fragment) as diagnostic/prognostic indicators of cell proliferative disorder ...
Apolipoprotein-A1 (Apo-A1)UrineBladder cancer is one of the tumors associated with the highest mortality rate. It is clinically characterized by high recurrent rates and poor prognosis once tumors invade the lamina propia. Nevertheless, current diagnostic techniques such as cystoscopy and cytology are...
Hence, directly targeting Apo A1 and Apo B would provide a better and safer option.Sharma, AditiSharma, ChakshuSharma, LalitWal, PranayMishra, PreetiSachdeva, NitinYadav, ShivamVargas De-La Cruz, CeliaArora, SandeepSubramaniyan, Vetriselvan...