Apolipoprotein-A1 (Apo-A1)UrineBladder cancer is one of the tumors associated with the highest mortality rate. It is clinically characterized by high recurrent rates and poor prognosis once tumors invade the lamina propia. Nevertheless, current diagnostic techniques such as cystoscopy and cytology are...
Using apolipoprotein A1 (Apo A1), a truncated form of transthyretin, ("transthyretin Delta N10) and/or a cleavage fragment of inter- alpha -trypsin inhibitor heavy chain H4 (IAIH4 fragment) as diagnostic/prognostic indicators of cell proliferative disorder ...
IntestineLipoproteinLiverRat apolipoproteins (apo-) A-IV and A-I share many structural similarities, the most notable of which is a domain of repeated ... NA Elshourbagy,MS Boguski,WS Liao,... - 《Proceedings of the National Academy of Sciences of the United States of America》 被引量:...
As a lipid transport protein, APOE3 and APOE2 preferentially bind to the smaller, more phospholipid-enriched high-density lipoproteins (HDL), while APOE4 preferentially binds to the larger, triglyceride-rich very low-density lipoproteins (VLDL). Miyata and Smith demonstrated an antioxidant activity ...
Aim: Determine the relationship between serum HDL-cholesterol levels and its subfractions (LpA-I and LpA-I/A-II) and apoprotein A1 (Apo A-I) and early high platelet reactivity (HPR) on clopidogrel in the acute phase of STEMI. Methods: Fifty-two patients (14 women and 38 men) aged ...
anaphylaxisapolipoprotein A1apolipoprotein Ebiomarkersmast cell activationAnaphylaxis is a life-threatening hypersensitivity reaction. To identify biomarkers for the condition, we assessed serum levels of apolipoprotein (Apo)A and ApoE. We found a reduction of both lipoproteins in anaphylactic mice as well ...
In addition, it also addresses how calculating Apo B:Apo A1 ratio can aid in analyzing the disease's risk. The marketed therapies available to control lipid abnormalities are associated with many other risk factors. Hence, directly targeting Apo A1 and Apo B would provide a better and safer ...
doi:US20080090223 A1The invention concerns a method for early diagnosis of hepatic diseases, which consists in determining in the samples of the diseased subjects, the presence of a apolipoprotein AI (Apo-AI) isoform, having oxidised W50, W108, and M112 residues. The inventive method is useful...
Lipids, lipoproteins, and apo- lipoproteins as risk markers of myocardial infarction in 52 countries (the IN- TERHEART study): a case-control study. Lancet. 2008;372(9634):224-233. 18. Hsia SH, Pan D, Berookim P, Lee ML. A population-based, cross-sec- tional comparison of lipid-...
The compounds of the present invention inhibit apolipoprotein B (Apo B) secretion and are useful as a medicament for prophylactic and treatment of diseases or conditions resulting from elevated circulating levels of Apo B.doi:EP1383760 A1TAKASUGI Hisashi...