(2010). The essential Escherichia coli apolipoprotein N-acyltransferase (Lnt) exists as an extracyto- plasmic thioester acyl-enzyme intermediate. Biochemistry 49, 341-346.Buddelmeijer N, Young R. The essential Escherichia coli apolipoprotein N-acyltransferase (Lnt) exists as an extra cytoplasmic ...
Conformational changes in Apolipoprotein N-acyltransferase (Lnt) Article Open access 20 January 2020 Author information Authors and Affiliations Department of Biochemistry, University of Missouri, Columbia, MO, USA Zachary T. Berndsen Department of Physics, University of Missouri, Columbia, MO, USA C...
Conformational changes in Apolipoprotein N-acyltransferase (Lnt) Benjamin Wiseman Martin Högbom Scientific Reports(2020) A sensitive fluorescence-based assay to monitor enzymatic activity of the essential integral membrane protein Apolipoprotein N-acyltransferase (Lnt) ...
In addition to apolipoproteins,HDLcontains an additional protein in the form of theenzymelecithin:cholesterolacyltransferase(LCAT), which esterifiescholesterol estersby transferring anLCFAmoiety fromphosphatidylcholine(lecithin) to cholesterol.LCATis activated by lipoprotein A-I. ...
Lipoproteins are virulence factors of Mycobacterium tuberculosis. Bacterial lipoproteins are modified by the consecutive action of preprolipoprotein diacylglyceryl transferase (Lgt), prolipoprotein signal peptidase (LspA) and apolipoprotein N- acyltransf
Depletion of Apolipoprotein N-Acyltransferase Causes Mislocalization of Outer Membrane Lipoproteins in Escherichia coli Lipoproteins in Gram-negative Enterobacteriaceae carry three fatty acids on the N-terminal cysteine residue, two as a diacylglyceride and one through an -l... C Robichon,D Vidal-Ingig...
Apolipoprotein AIV (apoAIV), a protein which is known to activate the enzyme lecithin: cholesterol acyltransferase, to bind to apoAI/AII receptor sites and... N Duverger,A Murry-Brelier,M Latta,... - 《European Journal of Biochemistry》 被引量: 66发表: 1991年 Mature apolipoprotein AI and ...
acyl CoA acyltransferase; apo, apolipoprotein; CE, cholesteryl ester; CM, chylomicron; COPII, coat protein complex II; DGAT, diglyceride acyltransferase; FA, fatty acids; FC, free cholesterol; FABP, fatty acid binding protein; MG, monoglyceride; MGAT, monoglyceride acyltransferase; MTTP, microsomal ...
1979. Effect of human plasma apolipoproteins on the activity of purified lecithin:cholesterol acyltransferase. Artery. 5: 61-75.Albers JJ, Lin J, Roberts GP. Effect of human plasma apolipoproteins on the activity of purified lecithin: cholesterol acyltransferase. Artery. 5:61-75, 1979....
The last step of this process, unique to Gram-negative bacteria, is the N-acylation of the terminal cysteine by Apolipoprotein N-acyltransferase (Lnt) to form the final mature lipoprotein. Here we report 2 crystal forms of Lnt from Escherichia coli. In one form we observe a highly dynamic ...