(that is, ± 2 kg), body composi- tion was measured by dual-energy X-ray absorptiometry (intelligent or iDXA, GE Healthcare, Little Chalfont, UK), which measures total body fat as well as android or central fat mass (starting above the pelvis), and gynoid fat mass (comprising the ...
Next, cells were reacted with Alexa Fluor® 647 Anti-Tubulin antibody (ab195884; Abcam, UK) at 4℃ overnight. A fluorescence microscope (200×, Ts2-FC; Nikon, Japan) was used to capture and observe the staining results. For colocalization, cells were incubated with rabbit anti-LUM (...
Sequences were detected on an ABI PRISM 3100 DNA sequencer, and results were analyzed with ABI PRISM SeqScape software (Applied Biosystems, Warrington, UK). Only a few members of the five kindred were available for DNA analysis. The APOB gene mutations found in the probands were screened in...
the human transgene, as well as rabbit IgG directed against the ERTARRLQAQAARRGY peptide (Neosystem, Strasbourg, France), referred to as E16Y, within the prodomain of PCSK9 were used to probe mouse liver proteins as described above using the ECL plus kit (Amersham, Little Shalfont, UK)...
The associations of the apolipoprotein B gene (APOB) rs693 and rs17240441 polymorphisms with plasma levels of APOB and lipids have been widely explored, but the results were inconclusive. This meta-analysis aimed to clarify the associations of the rs693
In addition, the apoB 48 postprandial response after a standardized mixed test meal was not improved in T/T subjects after the three-month diet, contrary to C allele carriers. Even though their phenotype at entry does not show any significant increase of risk factors when compared to other ...