Seventeen years ago, I sat down with Zhang Jiong, a man whose life was a poignant blend of adversity and unwavering hope. Diagnosed with chronic aplastic anemia, Zhang's story was not just about surviving; it was a...
doi:10.7754/Clin.Lab.2023.221220ACUTE myeloid leukemiaMONONUCLEAR leukocytesMYELODYSPLASTIC syndromesAPLASTIC anemiaREGULATORY T cellsBONE marrowKOUNIS syndromeDYSPLASIABackground: Systematic and comparative studies on CD4 T-lymphocytes in aplastic anemia (AA), myelodysplastic syndrome (MDS)...
Aplastic anemia (AA) is a kind of bone marrow failure (BMF) characterized by pancytopenia with hypoplasia/aplasia of bone marrow. Immunosuppressive therapy and bone marrow transplantation are effective methods to treat severe aplastic anemia. However, the efficacy is limited by complications and the ...
20, 25, 26 It also stimulates colony formation by precursor cells from patients with hypoproliferative disorders: Diamond-Blackfan anemia27, 28, 29 and AA.30, 31 Based on results of preclinical studies, a therapeutic value of SCF has been postulated.32, 33 To characterize the function of ...
Here, we present a case of severe aplastic anemia after hematopoietic stem cell transplantation with spurious high platelet count with normal histogram and no PLT flag(s). Methods: The electrical impedance channel (PLT-I) and the fluorescence channel (PLT-F) of Sysmex XN-series hematology ...
Abnormal metabolites related to bone marrow failure in aplastic anemia patients. Genet Mol Res. 2015;14(4):13709–13718. doi:10.4238/2015.October.28.33 (Open in a new window)PubMed (Open in a new window)Web of Science ®(Open in a new window)Google Scholar Li PL, Sun HG, Hua YL...
or treatment course. The main aim of this pilot study was to characterize the oral microbiome in patients with severe aplastic anemia (SAA) during their therapeutic course. SAA is a hematologic disease characterized by bone marrow failure which if untreated is fatal. Treatment includes either hemato...
Objectives: To investigate the immune status of children with very severe aplastic anemia (VSAA), and evaluate the frequencies of CD20(+) B cells and Regulatory T cells (Tregs) as potential markers for evaluating the therapeutic efficacy and prognosis. Methods: We systematically analyzed CD20(+) ...
Mean platelet volume and platelet distribution width are useful in the differential diagnosis of aplastic anemia and idiopathic thrombocytopenic purpura. Clin Chem Lab Med 2010;48:1675-1676.Lee WS, Kim TY. Mean platelet volume and platelet distribution width are useful in the differential diagnosis ...