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Selected parasite effector proteins that are examples of the different classes of proteins mentioned above are shown; that is, the rhoptry proteins, RON2 (host plasma membrane), ROP16 (host nucleus), toxofilin (host cytosol), and ROP17 (PVM); and the dense granule proteins, GRA1 (PV ...
Li H, Child MA, Bogyo M: Proteases as regulators of pathogenesis: examples from the Apicomplexa. Biochim Biophys Acta 2012, 1824:177-185.Li H, Child MA, Bogyo M. 2012. Proteases as regulators of pathogenesis: examples from the Apicomplexa. Biochimica et Biophysica Acta 1824:177-185. doi: ...
These examples are not easily explained by the “guilt by association”, or “stock and go” hypotheses of gene transcription. With the advent of ultra-high-throughput sequencing technologies there will be a quantum shift in transcriptional analysis which, combined with improving quantitative proteome...
Although 35 proteomic studies do not detect every gene for which transcripts are seen, many 36 examples of readily detected proteins, whose corresponding genes display little or no 37 detectable transcription are seen across the Apicomplexa. These examples are not 38 easily explained by the "guilt ...
The meaning of APICOMPLEXA is a taxonomic group and especially a phylum of diverse parasitic protozoans that have a complex life cycle usually involving both asexual and sexual generations often in different hosts, that move by gliding or bending, and th
Notwithstanding the above, there are strong arguments against the use of immunomicroscopy alone for definitive assignment of apical organellar components, borne out by those examples where otherwise well-characterised proteins have either been initially mis-localised (e.g. RESA; Refs. [9], [17], ...