(E) Quantification of the percentage of epithelium covered with apical Dp-YFP and basal Vkg-GFP in control wings, legs, and halteres at 4 and 7 hr APF. Average, SD, and individual data points are presented; n >
1976. Differential covalent labeling of apical and basal-lateral membranes of the epithelium of the toad bladder. J. Membrane Biol. 26:301-317Ekblad, E.B.M., Strum, J.M., Edelman, I.S. 1976. Differential covalent labeling of apical and basal-lateral membranes of the epithelium of toad ...
control mice in which CD71 was confined to crypt enterocytes, TyrA8-treated mice also expressed CD71 in the villous epithelium both at the apical and basal poles of enterocytes (Figure 2a). To confirm that CD71 was accessible from the luminal side after TyrA8 treatment, FITC (fluorescein ...
Loss of apical–basal polarity and activation of epithelial–mesenchymal transition (EMT) both contribute to carcinoma progression and metastasis. Here, we report that apical–basal polarity inhibits EMT to suppress metastatic dissemination. Using mouse
A Notch gradient along the apical-basal axis of the neuroepithelium is likely to play a key role in neurogenesis. Notch mRNA is increased on the apical side, whereas Delta mRNA and protein are enriched basally. This results in a gradient of Notch transcriptional activity, as demonstrated by ...
1978. Isolation of radioiodinated apical and basal-lateral plasma membranes of toad bladder epithelium. J. Membrane Biol. 45 :215Isolation of radio-iodinated apical and basal-lateral plasma membranes of toad bladder epithelium[J] . Hector J. Rodriguez,Isidore S. Edelman.The Journal of Membrane ...
B. Neurons arise in the basal neuroepithelium of the early mammalian telencephalon: a major site of neurogenesis. Proc. Natl Acad. Sci. USA 101, 3196–3201 (2004). ADS CAS PubMed Google Scholar Llorca, A. et al. Heterogeneous progenitor cell behaviors underlie the assembly of neocortical ...
5C). These data indicate that Cys-314 is acylated under basal conditions and that blocking acylation at this site may contribute to the reduction in ASBT transport function. However, as can be seen in Fig. 5C, there is a population of ASBT C314S that remains acylated, suggesting the ...
The formation of a tube lumen from a polarized epithelium can be achieved through several mechanisms, including wrapping, which produces a tube parallel to the original epithelial sheet. At the cellular level, these tissue behaviors require apical constriction, basal nuclear positioning and, in the ...
Fig. 1: The secretome from senescent cells suppresses apical extrusion of oncogenic RasV12-expressing MDCK cells from the surrounding normal epithelium. a–cPresenescent IMR-90 cells were rendered senescent by ectopic expression of oncogenicras(H-RasV12). These cells were then subjected to western...