show that basal stem cell progeny seamlessly integrate into a physiologically active barrier epithelium by gestating their future apical surface in a sheltering niche created by a transient occluding junction.doi:10.1038/s41556-023-01116-wAnthony,Galenza...
Our theoretical model to calculate the apical surface epithelial tension in a polarized epithelium from cell–cell adhesion and steady-state active prestress caused by myosin II activity using frequency shifts requires some critical assumptions. An important assumption is that a polarized confluent sheet ...
In DA-tube cells of brL>shi[K44A] egg chambers, we observed βPS-Integrin on the basal surface as in controls, but the pattern appeared more diffuse, basal puncta were less conspicuous, and cell outlines were more prominent than controls (compare Fig. 5E to F, G to H). Sub-basally,...
Loss of apical–basal polarity and activation of epithelial–mesenchymal transition (EMT) both contribute to carcinoma progression and metastasis. Here, we report that apical–basal polarity inhibits EMT to suppress metastatic dissemination. Using mouse and human epithelial three-dimensional organoid cultures...
Thus, pre-surface sterilization treatments have to be devised. For example, in guava, scions were obtained from selected field-grown plants and grafted to seedling root-stocks (Loh and Rao, 1989). Grafted plants were kept in the laboratory for harvesting nodal explants. To remove apical ...
(Barton2010). Bryophytes, the most basal group in the land plant lineage, spend most of their life cycle as gametophytes and it is in this phase that the SAM is formed. In contrast, seed plants spend most of their lifetime as sporophytes, thus, SAM formation occurs in the sporophytic ...
Differential signaling and regulation of apical vs. basolateral EGFR in polarized epithelial cells - Kuwada - 1998 () Citation Context ...en et al., 2002). Intriguingly, when EGFR is overexpressed in LLC-PK1 cells, a fraction of the receptor is mistargeted to the apical cell surface where ...
aThe majority of the cell's cytoplasm is occupied by mucinogen granules, except at the bottom. Rough endoplasmic reticulum, mitochondria, the nucleus, and other organelles are concentrated in the basal portion. The apical plasma membrane projects microvilli to increase surface area for secretion. Rec...
There are two distinct but interconnected systems - Planar cell polarity (PCP) and Apical-basal cell polarity (ABCP) that regulate the cellular spatial organization and alignment. Establishing and maintaining these cell polarity systems require dynamic interplay between the cell polarity signaling pathways...
shape factor estimated from a projected nuclear morphology onto theXY-plane depict a slight enlargement and elongation of the stretched nuclei (d,e). Nuclear volume and thickness (i.e., the maximum length from the basal surface to the apical surface) of the three-dimensionally reconstructed ...