Meta-analysis diag- nostic accuracy of SNP-based pathogenicity detection tools: a case of UTG1A1 gene mutations. Int J Mol Epidemiol Genet. 2013;4: 77-85.Galehdari H, Saki N, Mohammadi-Asl J, et al. Meta-analysis diagnostic accuracy of SNP-based pathogenicity detection tools: a case ...
A SNP was determined by the allelic discrimination method using fluorescence-labeled Taq-Man probes. Significant differences in the luciferaYasushiKawaguchiAkikoTochimotoMasakoHaraManabuKawamotoTomokoSugiuraEBSCO_AspImmunogeneticsKawaguchi Y, Tochimoto A, Hara M, Kawamoto M, Sugiura T, Saito S, et al....
The aim of this study was to investigate the possible association between two single-nucleotide polymorphisms (SNPs) of COL1A1, their haplotypes, and one SNP of JAG1 with BMD in postmenopausal Mexican-Mestizo women. Seven hundred and fifty unrelated postmenopausal women were included. Risk factors...
SummaryIn the present study, we assessed a SCN1A single nucleotide polymorphism (SNP) (rs3812718, IVS5N+5 G>A), first analyzed by Schlachter et al. We genotyped 164 patients with febrile seizures (FS) [of those 62 adults with focal epilepsy (FEFS+) and 102 children with pure FS (...
Sulfotransferase isoform 1A1 (SULT1A1) is the most highly expressed hepatic sulfotransferase and is involved in the biotransformation of a wide variety of endo- and xenobiotics. A common single nucleotide polymorphism (SNP) in the coding region of SULT1A1, several proximal promoter SNPs, and copy...
One key element in this search is the use of linkage disequilibrium to gain maximal information from typing a selected subset of highly informative single-nucleotide polymorphism (SNP) markers, now often called 'tagging SNPs' (tSNPs). Probably the most common approach to linkage-disequilibrium gene...
The minor G-allele of the HTR1A single nucleotide polymorphism (SNP) rs6295 attenuates firing of serotonergic neurons and reduces postsynaptic expression of the receptor. Experiments in rodents suggest that 5-HT1A-agonism modulates pain in opposite directions at mild compared to high noxious ...
, the presence of the A allele of SNP rs3812718 predicted non-retention (P&nbBo-Ting ZhouInstitute of Clinical PharmacologyQiu-Hong ZhouInstitute of Clinical PharmacologyJi-Ye YinInstitute of Clinical PharmacologyGuo-Liang LiInstitute of Clinical Pharmacology...
We found two nonsynonymous single nucleotide polymorphisms (SNPs) in the coding sequence of htr1A; one SNP close to a splice site in htr2A; and two SNPs in slc6A4, one in the coding sequence and one close to a splice site. In addition, we identified a polymorphic microsatellite marker ...
Single nucleotide polymorphism (SNP)UDP-glucuronosyltransferase 1ARecently, rs11892031[A] has been identified in a genome-wide association study (GWAS) to confer increased risk of urinary bladder cancer (UBC). To confirm this association and additionally study a possible relevance of exposure to ...