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Cloning and expression of APE, the cDNA encoding the major human apurinic endonuclease: definition of a family of DNA repair enzymes. Proc Natl Acad Sci USA. 1991;88:11450–4. Article CAS PubMed PubMed Central Google Scholar Li M, Wilson DM 3rd. Human apurinic/apyrimidinic endonuclease ...
APE1 is essential in cancer cells due to its central role in the Base Excision Repair pathway of DNA lesions and in the transcriptional regulation of genes involved in tumor progression/chemoresistance. Indeed, APE1 overexpression correlates with chemore
Analysis: DNA shows human-ape links, differencesROBERT SIEGEL
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We used two different lentivirus-mediated short hairpin RNAs (shRNA) against APE1 to knockdown its expression in the human cervix carcinoma cell line HeLa and SiHa. From here on, APE1 lentiviral negative control and APE1 knockdown cell lines are abbreviated as NC and shAPE1, respectively. In...
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Human APE1 ELISA Kit (人APEX核酸酶(多功能DNA修复酶)1) 本试剂盒仅用于科研,不能用于临床诊断,适用于血清、血浆、组织匀浆、细胞培养上清及其它生物体液。 现价:￥1800.00 货号:LV11038 规格: 96T 48T 数量 - + 加入购物车 说明书下载 产品参数 灵敏度检测范围 0.06ng/ml 0.31→20ng/ml 本试剂盒...
(redirected fromAPE1) APEX1 A gene on chromosome 14q11.2 that encodes a major apurinic/apyrimidinic (AP) endoDNAase, which is involved in the DNA base excision repair (BER) pathway of DNA lesions induced by oxidative and alkylating agents, and in the redox regulation of transcriptional facto...
适应物种:Human,Mouse,Rat,Chicken,Dog,Pig,Cow, 克隆性:是 标识物:各种标识物可定制 形态:liquid 保存条件:-20℃保存 是否进口:否 科淼生物简介 温州科淼生物科技有限公司(Whenzhou KeMiao Biological Technology Co.,Ltd)是一家专业从事“产品研发生产,市场销售,技术服务”为一体的高科技生物技术公司,致力于为科...