Genetic instability in colorectal cancers. Nature 386, 623–627 (1997).Colorectal tumours without microsatellite instability show a defect in chromosome segregation, resulting in gains or losses. This form of chromosomal instability persists throughout the lifetime of the tumour cell and is not simply...
A similar decrease was observed in two APC/C substrates, cyclin B1 and Aurora A, with a corresponding increase of CDH1 (Figure 5A) in the second cycle of the G1, suggesting that SAG could be a substrate of APC/CCDH1. Download: Download high-res image (1MB) Download: Download full-...
This inhibitor appears to be species-specific. CD59 is involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase. Defects in CD59 are the cause of CD59 deficiency (CD59D). Full Name CD59 molecule Research Areas...
Form Liquid Shipping This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. Storage This antibody can be stored at 2℃-8℃ for twelve months without detectable loss of activity. Protected from prolonged exposu...
Second, T cell responses to the full-length form of Topo I presented by dendritic cells were considerably lower than responses to Ag presented by PBMC APCs. Finally, no secondary T cell responses were observed unless the same Ag/APC combination as that used in the primary stimulation was ...
Annals of Pancreatic Cancer 2023; 6: 5 (15 June 2023) PDF Full Text (1461) Data Sharing Statement COI Form Open Access View more articlesJournal Highlight more Annals of Pancreatic Cancer is an international, open access, peer-reviewed journal for all researchers in the field of pancreati...
The full-length gels are presented in Supplementary Fig. 8. The As-CDC23 protein was expressed recombinantly via the pET28a vector. SDS-PAGE analysis showed the recombinant protein in Fig. 3a: The orders of Lanes are same as Fig. 2a, but Lane 6 shows the total proteins from ...
You may be required to register and activate access on Wiley Online Library before you can obtain the full text. If you have any queries please visit Wiley Online LibraryAbstract: Factor V is endowed with both procoagulant and anticoagulant properties. APC resistance caused by homozygous factor V...
A dimeric aggregate of KIR-HLA-C complexes was observed in one KIR2DL1-HLA-Cw4 crystal. Full Name killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 1 Research Areas Cancer>>Signal Transduction>>ITIM/ITAM Immunoreceptors and Related Molecules ...
We observed that HLA-DM+eAPC showed a dramatic improvement in their capability to present allergenic peptides derived from full-length Bet v 1 or birch pollen extracts (Fig. 7b). In a next step, we compared the stimulatory capacity of eAPCs (HLA-DRB1*07, CD80 and HLA-DM) with ...