2022年5月31日,来自同济大学生命科学与技术学院和附属东方医院再生医学研究所的魏珂教授团队在Cardiovascular Research发表题为“AP-1 activation mediates postnatal cardiomyocyte maturation”的论文[2]。该研究对出生后成熟过程中的大鼠心脏组织...
www.nature.com/scientificreports OPEN received: 16 April 2015 accepted: 16 July 2015 Published: 17 August 2015 Photodynamic activation as a molecular switch to promote osteoblast cell differentiation via AP-1 activation Toshihiro Kushibiki1,2, Yupeng Tu1, Adnan O. Abu-Yousif1 & Tayyaba...
Photodynamic activation as a molecular switch to promote osteoblast cell differentiation via AP-1 activation. Sci Rep 2015; 5: 13114.T. Kushibiki, Y. Tu, A. Abu-Yousif, T. Hasan: Photodynamic activation as a molecu- lar switch to promote osteoblast cell differentiation via AP-1 activation. ...
The AP-1 activation mainly depends on all of the β-sheet barrel on SPRY structure of TRIM5α. Furthermore, the SPRY-mediated auto-ubiquitination of TRIM5α is required for AP-1 activation. This study reports that rhesus macaque TRIM5α mainly undergoes Lys27-linked and Met1-linked auto-...
In addition, the lack of zygotic c-Jun transcripts until the end of gastrulation should exclude a role of AP-1 in the activation and the early expression of BMP-4 during gastrulation in vivo. However, at later stages of Xenopus development, we find a spatial overlap of c-Jun and BMP-4...
Regulation of TGF-alpha-induced activation of AP-1 in the aging gastric mucosa. Although the age-related activation of EGF receptor (EGFR) in the gastric mucosa of Fischer 344 rats is associated with increased DNA binding activity of a... Xiao, Zhi-Qiang,J Li,APN Majumdar - 《Ajp Gastroin...
Tumor Necrosis Factor-α Inhibits Transforming Growth Factor-β /Smad Signaling in Human Dermal Fibroblasts via AP-1 Activation Understanding the molecular mechanisms underlying the antagonistic activities of tumor necrosis factor-alpha (TNF-alpha) against transforming growth factor......
[22]HUANG Q Y, DU X X, HE X, et al. JNK-mediated activation of ATF2 contributes to dopaminergic neurodegeneration in the MPTP mouse model of Parkinson’s disease[J]. Exp Neurol, 2016, 277: 296-304. [23]ZENG X S, JIA J J, KWON Y, et al. The role of thioredoxin-1 in suppres...
c-Jun N-terminal kinase activation of activator protein-1 underlies homologous regulation of the gonadotropin-releasing hormone receptor gene in alpha T3-1... Reproductive function is dependent on the interaction between GnRH and its cognate receptor found on gonadotrope cells of the anterior pituitar...
AP-1/NF-κB activation inhibitor 1 是一种有效的 AP-1 和 NF-κB 介导的转录激活抑制剂(IC50=1 μM),不阻断 β-actin 启动子驱动的基础转录。AP-1/NF-κB activation inhibitor 1 对受刺激细胞产生IL-2和IL-8水平有相似的抑制作用。 AP-1/NF-κB activation inhibitor 1名称 ...