A Phase III study on ApoE4-bearing AD patients using CSP-1103 (the new denomination of CHF5074) is planned for the near future [97]. Second generation, more potent, neutral non-NSAID GSMs cause the simultaneous increase of Aβ37 (ɛ-cleavage of Aβ40) and Aβ38 (ɛ-cleavage of ...
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