In addition, PSE inhibited the transcriptional activity of NFAT without interfering with the calcium-induced NFAT dephosphorylation event, which represents the major signaling pathway for its activation. NFAT cooperates with c-Jun, a compound of the AP-1 complex, to activate target genes, and we ...
ExpressionthroughthePKC�/c-Src/EGFR/PI3K/Akt/AP-1 SignalingPathwayinHumanChondrocytes Chun-YinHuang, 1,2,3 Hsiu-JungLin, 4 Hsin-ShuiChen, 3,5 Shi-YannCheng, 3,6 Horng-ChaungHsu, 3,7 andChih-HsinTang 3,8,9 1 GraduateInstituteofClinicalMedicalScience,ChinaMedicalUniversity,aichung,aiwan ...
AP一1cellsignalingpathwaychangeinhumanembryoniclungfibroblasts(HELFs) inducedbysilica.Methods CpstimulatedHELFsindiferenttimepoints(before1h, accompaniedwithorafter1hofsilica—adding).HELFsweredividedintothesegroups: controlgroup,silica(100I~g/mlfor24h)group,Cp(30I~g/mlfor24h)groupand ...
Cell Death Dis 2010; 1: e23Brandt B, Abou-Eladab EF, Tiedge M, Walzel H. Role of the JNK/c-Jun/AP-1 signaling pathway in galectin-1-induced T-cell death. Cell Death Dis 2010;1:e23.B. Brandt, E. F. Abou-Eladab, M. Tiedge, and H. Walzel, "Role of the JNK/c-Jun/AP-...
实验解读,给了signaling pathway的图,和不同物种(none,human,物种A,物种B)来源的aquaporins和H2O2的passing rate之间对比的数据表。 -考察water transport across aquaporin,问substance transport在同时含有aquaporins和phospholipid的细胞中发生时aquaporin的优点。 -问这四个中哪个aquaporins和物种B的不同,实则考察statistica...
Paul1,2, K. Demuth1,2. 1Biochimie Cardio-Vasculaire, Hpital Europeen G. Pompidou, Paris; 2Biochimie Appliqu... 1 signaling pathway Homocysteine decreases endothelin-1 expression by interfering with the AP-1 signaling pathwayHomocysteine decreases endothelin-1 expression by interfering with the AP-...
1 signaling pathway Homocysteine decreases endothelin-1 expression by interfering with the AP-1 signaling pathwayHomocysteine decreases endothelin-1 expression by interfering with the AP-1 signaling pathwaydoi:10.1016/S1567-5688(02)80173-8SDOSAtherosclerosis Supplements...
关键词:PPAR -γ;AP -1;信号通路;疾病中图分类号:R392. 9 文献标识码:A 文章编号:1671 -380X (2021)06 -0012 -05Progress on the Role of the PPAR -γ /AP -1 Signaling Pathway in Related DiseasesLIU Dong - Mei 1 ,XIAO Mei - xian 2 ,WANG Hai - li 1 ,ZHAO Xiao - jie 1 ,HAN ...
[CG]TCA-3'. It promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. JUN is a basic leucine zipper (bZIP) transcription factor that acts as homo- or heterodimer, binding to DNA and regulating gene ...
At the same time,TNF-α activated the expressions of NF-κB and AP-1( P 0. 05). Conclusion TNF-α significantly increases the apoptosis and inflammation of HUVECs. The mechanism of this injury might be related to the activation of the NF-κB and AP-1 signaling pathway and inhibiting ...