doi:10.1002/9781444346343.ch4FRACP Edmund Tse MBBSMichael R. Beard PhDWiley‐BlackwellShiraki K, Daikoku T, Takemoto M, Himaki T, Kuramoto T. Mechanism of action of antiviral drugs. Nihon Rinsho. 2012; 70: 545-551.
Homology models of the HIV-1 attachment inhibitor BMS-626529 bound to gp120 suggest a unique mechanism of action Proteins, 83 (2015), pp. 331-350 Google Scholar Lataillade et al., 2018 M. Lataillade, N. Zhou, S.R. Joshi, et al. Viral drug resistance through 48 weeks, in a phase...
In today’s global society, disease outbreaks can spread rapidly and easily cross borders and continents, having a catastrophic impact on health and the global economy. There is no single solution to prevent the spread of viral infections. Different modes of infection transmissions such as through ...
MECHANISMS OF ANTIVIRAL ACTION 来自 Elsevier 喜欢 0 阅读量: 19 作者: RM Friedman 摘要: Interferon induces reversion of RAS-transformed fibroblasts. The mechanism appears to involve the induction of prolysyloxidase. We are investigating the mechanism of this induction process. DOI: 10.1016/B978-...
4.1. General mechanism of action The mechanisms of antiviral drugs action are mainly acting on the virus itself or acting on the host. Also, antiviral drugs act on various enzymes related to transcription and replication to destroy the viral pathogen or inactivate its infectivity (Vilas Boas et ...
药理学英文版教学课件:Chapter 42 Antiviral-antifungal drugs.ppt,* * * * * * * * * * * * * * * * * * * * * * Acyclovir, ACV (阿昔洛韦) Mechanism of action After converted the triphosphate form, the drug interferes with herpes simplex virus(单纯疱疹病毒)
In addition to discriminating between cellular toxicity and specific activity directed against a viral target, drug resistant mutants have been used to confirm the mechanism of action of antiviral drugs, to discover the functions of several viral proteins and to provide insights into viral evolution ...
Discusses the differential antiviral mechanism of action on the RdRp in causing downstream mutagenesis. CAS PubMed PubMed Central Google Scholar Vegivinti, C. T. R. et al. Efficacy of antiviral therapies for COVID-19: a systematic review of randomized controlled trials. BMC Infect. Dis. 22,...
Antiviral drug, any agent used in the treatment of an infectious disease caused by a virus. Antiviral agents generally are designed to block viral replication or disable viral proteins. Examples of antiviral drugs include agents to combat herpes viruses,
DrugVirusMechanism of ActionClinical StatusReferences MaravirocHIVBlocks CCR5 coreceptorApprovedFatkenheuer et al. (2005) Cyclosporin A and related compoundsHCVBinds and inactivates cyclophilin A, acis–trans isomerasePhase III trialsLin and Gallay (2013) ...