With the aim of obtaining azo dyes with high chemotherapeutic properties, two groups of azo dyes were prepared for studies, namely, (1) monazo dyes by the diazotization of sulfa drugs and related amines and then coupling with bis(4-aminophenyl)-sulfone, and (2) bisazo dyes by the tetra...
The antitubercular activity of azo dyes. II. Monazo dyes derived from diazotized sulfa drugs and bis (4-aminophenyl)-sulfone and bisazo dyes from tetrazotized bis (4-aminophenyl)-sulfone and sulfa drugsdoi:10.1002/recl.19500691111Peter P. T. Sah...
With the aim of obtaining azo dyes with high chemotherapeutic properties, two groups of azo dyes were prepared for studies, namely, (1) monazo dyes by the diazotization of sulfa drugs and related amines and then coupling with bis(4-aminophenyl)-sulfone, and (2) bisazo dyes by the tetra...
TPSA has been used as descriptor for characterizing absorption and passive transportation properties through biological membranes, allowing a good prediction of transport of candidate drugs in the intestines and through the blood-brain barrier (BBB). TPSA is sum of van der Waals surface areas of ...
tuberculosis from the host tissues and to prevent the relapse of TB, there is a need to identify novel anti-TB drugs targeting replicating and nonreplicating stages of the bacillus. TB drug discovery and development has made great progress in the past 20 years in part owing to the deciphering...
Introduction There is an urgent need to develop new drugs for the treatment of tuberculosis (TB), a chronic disabling infection caused by Mycobacterium tuberculosis (Mtb). This pathogen has developed resistance to standard first- and second-line anti-TB drugs, leaving very few options for ...