Data were collected a year before the FDA issued black box warnings for the potentially unsafe off-label usage of atypical antipsychotics for dementia. Of the estimated 690 000 residents with dementia, 31.6% were found to be taking atypical agents, dwarfing typical agent use of 1.75%. Olanzapine...
BACKGROUND: In April 2005, the US Food and Drug Administration (FDA) issued an advisory and subsequent black box warning regarding the risks of atypical anti psychotic use among elderly patients with dementia. The impact of these warnings on atypical drug use is unknown. METHODS: We used quasi...
The 2005 US Food and Drug Administration (FDA) black-box warning about increased mortality being linked to atypical antipsychotic (AAP) use in elderly patients with dementia may have had unintended consequences. However, at this point, the findings are "hypothesis generating," and more research is...
Because of pharmacodynamic and pharmacokinetic changes associated with aging, there are many more risks attendant to treating elderly patients with psychotropics. The FDA has recently issued black box warnings for older adults who may be... T Meeks 被引量: 0发表: 2010年 加载更多研究...
This class of medications also carries FDA black box warnings due to increased risk of death in elderly patients. Clinical reports indicate that patients treated with these medications are more susceptible to infections; however, the underlying mechanisms/pharmacology are unclear. We have previously ...
Impact of the Food and Drug Administration's antipsychotic black box warning on psychotropic drug prescribing in elderly patients with dementia in outpatie... Background Most patients with dementia also suffer from behavioral and psychological symptoms of dementia, for which there is no Food and Dru...
These drugs carry a black box warning from the U.S.Food and Drug Administrationthat they cause death indementia patients, Curry said. "Advocates welcome every step taken to raise awareness about the dangers, to end unnecessary drugging and the harm it brings residents and to strictly enforce ru...
Impact of the Food and Drug Administration's antipsychotic black box warning on psychotropic drug prescribing in elderly patients with dementia in outpatient and office-based settings. Alzheimers Dement. 2012;8(5):453-7.Desai VC, Heaton PC, Kelton CM. Impact of the Food and Drug Administra- ...
In April 2005, the Food and Drug Administration (FDA) issued a black box warning (BBW) regarding the risks of using atypical antipsychotics (AAPs) for behavioral disorders in elderly patients with dementia. The objective of the present study was to investigate the impact of the BBW on the ...
doi:10.1016/j.jval.2011.02.042V.C.DesaiandP.C.HeatonandC.KeltonSDOSValue in Health