Antiplatelet Therapy After TAVR: More ARTE Than ScienceZimmet, JeffreyClinical Cardiology Alert
To better understand the role of antiplatelet therapy after TAVR, two larger-scale trials, POPular-TAVI and CLOE, will evaluate aspirin therapy alone versus aspirin and clopidogrel therapy in the first 3 months after TAVR [137]. Notably, anticoagulation therapy appears to more effectively prevent ...
Dual or Single Antiplatelet Therapy After Transcatheter Aortic Valve Implantation? A Systematic Review and Meta-Analysis Dual or single antiplatelet therapy after transcatheter aortic valve implan- tation? A systematic review and meta-analysis. Curr Pharm Des 2016; 22: 4596-... D Tousoulis,C ...
H. et al. Apixaban, an oral, direct, selective factor Xa inhibitor, in combination with antiplatelet therapy after acute coronary syndrome: Results of the Apixaban for Prevention of Acute Ischemic and Safety Events (APPRAISE) trial. Circulation. 119, 2877–2885 (2009). Article PubMed Google ...
Keywords: percutaneous coronary intervention / dual antiplatelet therapy / aspirin / P2Y12 receptor inhibitor References [1] Leon MB,Baim DS,Popma JJ,et al.A clinical trial comparing three antithrombotic-drug regimens after coronary-artery stenting.Stent Anticoagulation Restenosis Study Investigators[J...
TAVRCurrent guidelines recommend a three-to six-months dual antiplatelet therapy (DAPT) in patients undergoing transcatheter aortic valve replacement (TAVR) or to continue with oral anticoagulant agents (OAC) if already indicated before procedure. However, recent studies showed that treatment with ...
Among patients who underwent TAVR, DAPT compared to SAPT had similar rates of stroke, myocardial infarction and death. Due to lower rates of bleeding, we recommend using single antiplatelet therapy after TAVR. FUNDING ACKNOWLEDGEMENT. Type of funding sources: None....
Johny NicolasZena and Michael A. Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USAGeorge DangasZena and Michael A. Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA...
dual anti-platelet therapy (DAPT) after transcatheter aortic valve replacement (TAVR). The optimal antiplatelet regimen post TAVR remains uncertain. Methods: Electronic databases were searched for randomized and observational studies, which compared SAPT versus DAPT after TAVR. The primary outcomes were....
particularly in patients who do not have a preexisting or concurrent comorbidity which requires long-term anticoagulation therapy.#Methods:We performed a systematic review and meta-analysis to compare Direct Oral Anticoagulants (DOACs) versus antiplatelet therapy after TAVR in patients without previous ind...