A positive ANA test suggests the presence of autoantibodies, which can be associated with autoimmune diseases such as lupus, Sjögren's syndrome, juvenile arthritis, polymyositis,dermatomyositis, and scleroderma. It is important to note that a positive result is not definitive for any specific ...
Antinuclear Antibody-Positive Juvenile Idiopathic Arthritis Despite IRAK-4 DeficiencyANTINUCLEAR factorsJUVENILE idiopathic arthritisINTERLEUKIN-1 receptorsUnlabelled: IRAK-4 deficiency causes IL-1R and TLR signaling failure, resulting in minimal clinical features despite invasive bacterial infection. We report ...
There is no doubt that in some cases of autoimmune disease one method may detect an antibody prior to another. However, the claim that greater than 90% of ANA samples should be positive at the time of diagnosis of conditions such as SLE is not consistent with more recent knowledge of the...
A 43 year old woman who initially presented with the nephrotic syndrome, glomerulonephritis, and antinuclear antibodies (ANAs) was given the diagnosis of systemic lupus erythematosus (SLE). One year later the patient developed progressive subcutaneous nodules on her forearms, with histopathology of non...
antibody and the pm-1 antibody was found in patients with cutaneous muscle. Patients with multiple myotypes were determined to have a positive positive rate of 13.6%, skin muscle (DM) 20%, systemic sclerosis and 25% of myositis, SLE
Twelve events occurred in 11 women with positive antinuclear antibody but negative anti-DNA antibody test reactions and no other manifestation of SLE. Of the remaining... Kaell,Alan,T. - 《Archives of Neurology》 被引量: 145发表: 1986年 Autoantibodies in black South Africans with systemic lupus...
The aim of this study is to evaluate the relationship between antinuclear antibody (ANA) titer and specificity, as well as the relationship between the number of positive-autoantibodies (AAbs) in antinuclear antibodies (ANAs) and specificity for systemic
Because trial results suggest that patients who are ANA negative might not respond to certain agents, screening strategies now involve ANA and anti-DNA antibody testing to identify patients with so-called ‘active, autoantibody-positive SLE’. Evidence suggests that ANA responses can decrease over ...
Mariz HA, Sato EI, Barbosa SH et al (2011) Pattern on the antinuclear antibody-HEp-2 test is a critical parameter for dis- criminating antinuclear antibody-positive healthy individuals and patients with autoimmune rheumatic diseases. Arthritis Rheum 63:191-200...
Key: ANA = antinuclear antibody, ANA-positive = titers ≥1:80, ANA-negative = titers <1:80, HCV = hepatitis C virus, HCV-1 = with HCV genotype 1 infection, HCV-non 1 = without HCV genotype 1 infection, SVR = sustained virological response. Table 5. Stepwise logistic regression analysis...