Each of these agents has very different and unique biological mechanisms of action; yet, when used alone or in combination, these drugs have historically proven to be clinically effective in the acute treatment and long-term public health management of Mycobacterium infections such as tuberculosis ...
The implications of QSAR data for the rational design of new antituberculosis agents are discussed. Because mycobacteria degrade steroids to progesterone-type compounds, unambiguous assignments of the high-field proton ( 1 H) and carbon-13 ( 13 C) NMR data of progesterone ( 1 ) were achieved ...
Access the complete reference list online at http://www.expertconsult.com This chapter provides an overview of major antibacterial, antimycobacterial, antifungal, and antiviral agents but does not include comprehensive information about the pharmacology, indications, dosing, or toxicities of all the ...
Medicinal plants from open-air markets in the State of Rio de Janeiro Brazil as a potential source of new antimycobacterial agents. J. Ethnopharmacol. 149 (2), 513-21.Medicinal plants from open-air markets in the State of Rio de Janeiro, Brazil as a potential source of new antimycobacterial...
Our future endeavors aim to produce more potent derivatives of this compound while preserving its low toxicity. In essence, derivatives of quinoxaline-2-carboxylic acid 1,4-dioxide stand out as a promising foundation for the formulation of advanced antimycobacterial agents....