细菌耐药性(英文PPT)Antimicrobial Resistance THEU.S.MEDICINEINSTITUTEFORHEALTHSTUDIES AddressingAntimicrobialResistance Washington,DC February9,2007 DonaldM.Poretz,MD,FACP,FIDSA PlanetEarth Microbes HumanBeings Number 5x1031 6x109 MetricTons 5x1016 3x108 Replicate20-30minutes 20-30years Microbiologyinthe21st...
细菌耐药性(英文PPT)Antimicrobial ResistancePPT.ppt,THE U.S. MEDICINE INSTITUTE FOR HEALTH STUDIES Addressing Antimicrobial Resistance Washington, DC February 9, 2007 Donald M. Poretz, MD, FACP, FIDSA;Planet Earth;Microbes;Human Beings;Underlying Princi
抗生素英文精品 Antimicrobial Resistance(AMR)课件 AntimicrobialResistenceSurveillenceInNepal ForRationalUseofAntibiotics WorldHealthDay7thApril,2011 Dr.GeetaShakyaDirector,NPHL,Teku AntimicrobialResistance(AMR)➢Oneofthemajorchallengesfacingpublichealthinthiscentury ➢athreattocurrentandfuturemedicaladvances➢Bigger...
细菌耐药性(英文PPT)Antimicrobial Resistance THEU.S.MEDICINEINSTITUTEFORHEALTHSTUDIES AddressingAntimicrobialResistance Washington,DC February9,2007 DonaldM.Poretz,MD,FACP,FIDSA HumanBeings Canaffecttherateofspreadofbacterialresistancebyapplyingselectivepressureviaexposuretothethousandsofmetrictonsofantibioticswehave...
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strains of MRS, allβ-lactams antimicrobial drugs is resistance,regardless of result of test in vitro.frequently,multiple drug resisitance appeared in many other drugs. Therapy drugs could selected :vancomycin, linezolid,daptomycin…… 2)Penicillin resistance of staphylococcus-β-lactamase The resistance...
Resistance (cont.) ? Dose of drug has to be sufficient to produce effect inhibit or kill the microorganism: ? However concentration of the drug must remain below those that are toxic to human cells – ? If can be achieved – microorganism susceptible to the ATB ? If effective concentration ...
1、,Antimicrobial Susceptibility Testing and bacterial drug resistance,1 Concept :,1). antibiotic 2). antibacterial agents 3). Zone Diameter 4). minimal inhibitory concentration 5). minimal bactericidal concentration 6). Post antibiotic effect 7). -lactamase 8) .-lactamase inhibitor,1)antibiotics ...
Quinolone resistance among Shigella spp How to evaluate and predict the ecologic impact of antibiotics: the pharmaceutical industry view from research and development R. Bax Clinical Microbiology. Chlamydia trachomatis infections in heterosexuals attending sexually transmitted disease clinics in Slovenia D. ...
microbe • Increase in MIC • Enzymatic destruction of drug • Prevention of penetration of drug • Alteration of antibiotic or target site • Rapid ejection of the drug Mechanisms of Antibiotic Resistance Antibiotic Selection for Resistant Bacteria What Factors Promote Antimicrobial Resistance?