Mechanism of actionBiological activityClinical applicationThe management of bacterial infections is becoming a major clinical challenge due to the rapid evolution of antibiotic resistant bacteria.As an excellent candidate to overcome antibiotic resistance,antimicrobial peptides(AMPs)that are produced from the ...
aThe mechanism of action of the antimicrobial peptides is notentirely clear. Interactions between peptides and cell membraneswere believed to be an important step in the mechanistic process 抗菌肽的行动机制是notentirely清楚的。 肽和细胞membraneswere之间的互作用在机构过程中相信是重要步[translate]...
The management of bacterial infections is becoming a major clinical challenge due to the rapid evolution of antibiotic resistant bacteria. As an excellent candidate to overcome antibiotic resistance, antimicrobial peptides (AMPs) that are produced from the synthetic and natural sources demonstrate a broad...
M. Wu, E. Maier, R. Benz and R.E.W. Hancock: “Mechanism of interaction of different classes of cationic antimicrobial peptides with planar bilayers and with the cytoplasmic membrane ofEscherichia coli”,Biochemistry, Vol. 38, (1999), pp. 7235–7242. ArticlePubMedCASGoogle Scholar R.M. ...
The innate immunity modulates its antimicrobial functionality by small cationic peptides with activity against gram-positive and negative bacteria, parasites, fungi and some viruses (Akalin et al., 1993, Allaker et al., 1999, Allgrove et al., 2008). The mechanism of action against microbes ...
Some of the recent strategies developed to improve the activity and biocompatibility of AMPs, such as chemical modifications and the use of delivery systems, are also reviewed in this article. 展开 关键词: antimicrobial peptides mechanism of action chemical modification delivery systems bioconjugation ...
Cationic host defence peptides (CHDP), also known as antimicrobial peptides, are naturally occurring peptides that can combat infections through their direct microbicidal properties and/or by influencing the host’s immune responses. The unique ability of CHDP to control infections as well as resolve...
Antimicrobial peptides are membrane active polypeptides with important functions in the innate host-defense system of many organisms [1–8]. The structural mechanisms underlying their mode of action requires improved structural characterization on the molecular scale. Some of the structural models discussed...
Antimicrobial peptides Mechanism of action Antimicrobial resistance Peptide drug Bacterial infection Sorry, something went wrong. Please try again and make sure cookies are enabled Data availability No data was used for the research described in the article.Cited...
Herein, we characterized a novel antimicrobial peptide called Pinipesin, present in the exuviae extract of the centipede. The antimicrobial activity of Pinipesin was tested. The haemolytic activity of the peptide was evaluated and its possible mechanism of action was investigated. Identification was ...