The differences with regard to safety among the second-generation antihistamines are smaller than are the differences between the first and second generations. A nonsedating, nonimpairing (even at higher than recommended doses), second-generation antihistamine is preferred for all patients, particularly...
If you take other drugs that can make you drowsy, such as sedatives or tranquilizers, talk to your doctor before using first-generation antihistamines. You should also avoid drinking alcohol with any antihistamine because it can increase the side effect of drowsiness. Second- and third-generation...
The first generation of OTC oral antihistamines include chlorpheniramine and diphenhydramine. They are amongst the oldest group of antihistamines. They sedate a person, leading to extreme cases of drowsiness. These antihistamines do not last long in the system, hence, there is a more frequent urge ...
There are significant differences between first-generation antihistamines and second-generation antihistamines. The older first-generation agents tend to not only cause drowsiness but also cause abnormalities in psychomotor performance as reflected by impairment in driving, school performance impairment and ...
1 Antihistamines can be divided into first and second-generation (also called nonsedating) agents (Table 1). First-generation antihistamines are small lipophilic molecules, so they may cause adverse effects because of their cholinergic activity and their ability to cross the blood-brain barrier. ...
3.The efficacy and safety of the third generation antihistamine desloratadine in clinical use;第三代抗组胺药地氯雷他定 英文短句/例句 1.azatadine maleate(抗组胺药) 马来酸哌吡庚啶 2.an antihistamine with the trade name Coricidin.商标名为柯利西锭的抗组胺药。 3.Analysis of the Second-Generatio...
We discuss types of histamine receptors and their mechanism of action, absorption, onset and duration of action of first-generation and second-generation H(1)-antihistamines, as well as elimination of H(1)-antihistamines which has important implications for dosing in children. The rationale for ...
Second-generation H(1)-antihistamines are preferable to first-generation H(1)-antihistamines in the management of non-anaphylactic allergic reactions, AR, AE and CSU due to: their better safety profile, including minimal cognitive and antimuscarinic side effects and a longer duration of action. We...
1) Second generation antihistamine drugs 第二代抗组胺药 2) second 第二 1. Relationship between abnormal fetal heart rate tracing patterns during thesecondsteage of labor and perinatal outcome; 第二产程异常胎心监护图形与新生儿结局的关系 3) Second industry ...
The centrally acting first-generation agents, and the performance decrements these agents commonly induce, are compared with the newer, nonsedating, second-generation antihistamines (eg, terfenadine, astemizole, cetirizine, and loratadine). Although decongestants do not appear to cause impaired ...