Explore the mechanism of antigenic shift through examples. See the antigenic shift definition and understand what contributes to this process in...
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harbour their own strains of influenza A virus. Recombinants between different type A influenza viruses are readily formed because the influenzavirus genomeconsists of eight segments which can re-assort independently of each other. To be of pandemic potential,antigenic shiftmust involve the RNAs encodi...
. Second injection of any other NTD Fabs hardly elicited wavelength shift, indicating that their binding was blocked in the prior presence of D12 (or F07) (Fig.1c, d). Moreover, concurrent binding was not observed between F07 and D12 either (Fig.1c, d). Together, these results impli...
The analysis was performed considering all the overlapping nonamers with a one-amino-acid lateral shift covering the entire protein sequence. In order to select the best predicted epitopes, we focused our analysis only on those showing an affinity < 100 nM to HLA molecules, which we have ...
the variants NP, dinitrophenyl (DNP) and trinitrophenyl (TNP) (Fig.6a). ACKR4+/−mice were immunized with NIP-KLH. After the onset of BEMrecycling, we rechallenged in the same foot with NP, DNP, followed by TNP-KLH. Three days after the last injection we observed a shift in ...
Although the high level of Blimp-1 expression by TI BM plasma cells was one element in favour of their maturity, it was of crucial importance to bring additional proof that the NP-binding ASCs we analysed in the BM after NP-dextran immunization fulfill the definition of mature plasma cells....
First (i), some sites showed complete replacement of the TF form with another single variant, whether fast or slow, e.g., the shift of a glycosylation site from position 334 to 332 (top-right panel "N332" in Figure 2, NÑO, and O334 in the next row, from OÑS, where "O" ...