The medicament containing above recombinant protein as active component has significant selective inhibitory effect on tumor cells, and does not induce apoptosis of normal tissue cells, and has important applicable value.doi:CA2544473 CBing ZhuCA...
3. Cross CE, vd VA, O'Neill CA, Eiserich JP: Reactive oxygen species and the lung. Lancet. 1994, 344: 930-933. 10.1016/S0140-6736(94)92275-6.PubMedCrossRef 4. Day BJ: Antioxidants as potential therapeutics for lung fibrosis. Antioxid Redox Signal. 2008, 10: 355-370. 10.1089/ars....
City of Hope Graduate School of Biological Sciences, City of Hope National Medical Center, Duarte, CA, USA J Zhang & J J Rossi Department of Medical Microbiology, Academic Medical Center of the University of Amsterdam, Amsterdam, The Netherlands K J von Eije Department of Computer and Informati...
RNA integrity was assessed using the RNA Nano 6000 Assay Kit of the Bioanalyzer 2100 system (Agilent Technologies, CA, USA). Sample preparation for sequencing A total amount of 3 μg RNA per sample were used as input material for the RNA sample preparations. All four samples had RNA ...
Unconjugated SSO-1 and 5′-aminolinker C6 precursors (for SSO-2–5) were synthesized on NittoPhase HL UnyLinker 350 support (Kinovate, Oceanside, CA) on an ÄKTA Oligopilot (GE Healthcare, Brondby, Denmark) at 130 μmol scale. After synthesis, the oligonucleotides were cleaved from the ...
For the SCD mutation introduction, the ribonucleoprotein complex (RNP) was first formed by incubation of guide RNA (200 pmol; Synthego, CA, USA) (5′-GUA ACG GCA GAC UUC UCC UC-3′) and Cas9 protein (200 pmol; UC Berkeley, Berkeley, CA, USA) at room temperature for 15 min. HUDEP...
This work was supported in part from Leukemia and Lymphoma Society Specialized Center of Research (SCOR; Grant no. 7018), the NIH Grants PO1CA94237, P50CA126752 and RO1CA131027, Leukemia and Lymphoma Society Translational Research grants, Doris Duke Charitable Foundation/Clinical Scientist develop...
The transplanted tumors formed into nude mice were injected with AxCA‐cp53, AxCA‐LacZ (adenovirus vector expressing LacZ) or PBS (3 mice each) 7 times during 15 days. Tumor sizes were measured every 3 days for 27 days after injection with the adenovirus vectors. Expression efficiency of ...
The present invention provides an antibody that specifically binds to human ADAM28, inhibits enzyme activity of human ADAM28, and has an activity to suppress metastasis of a cancer
4 Flow cytometric analysis of the effects of DADS on N18’s Ca 2+ concentration and apoptosis. The N18 cells were incubated with various concentrations of...Bottone FG Jr,BaeK SJ,Nixon JB,et al.Diallyl disulfide ( DADS)induces the antitumorigenic NSAID -activated gene ( NAG -1 ) by a ...