Microfluorometry on antigen-antibody interaction in immunofluorescence using antigens covalently bound to agarose beads. J. Immunol. Methods 2:383-392.van Dalen, J. P. R., W. Knapp, and J. S. Ploem. 1973. Microfluorometry on antigen-antibody interaction in immunofluorescence using antigens ...
The binding of an antigen and antibody is described as theprimary interaction. This occurs as a result of a good fit between the antigen-binding site on the Fab portion of the immunoglobulin molecule and the epitope present in the antigen. As a consequence of this binding many secondary phenom...
Conformational changes in the antibody constant domains upon hapten-binding a lower Ka value for the interaction with IgG2a, it was shown that hapten-binding induced long range conformational changes in the Fc region of IgG2a. ... Takuma Sagawa and Masayuki Oda and Hisayuki Morii and Hisao Takiza...
Role of Salt Bridge Formation in Antigen-Antibody Interaction: ENTROPIC CONTRIBUTION TO THE COMPLEX BETWEEN HEN EGG WHITE LYSOZYME AND ITS MONOCLONAL ANTIBODY HyHEL10 喜欢 0 阅读量: 25 作者:Tsumoto,K.,Ogasahara,K.,Ueda,Y.,Watanabe,K.,Yutani,K....
This stimulation can result in both a proliferation of antigen specific lymphocytes and differentiation of lymphocytes into plasma cells that secrete antigen-specific immunoglobulins ("antibodies"). A second role of immunoglobulins is to serve as the effector substances which, upon interaction with the ...
In this case, the 'instability' of the SIP- drug interaction may actually result in quicker drug release in the tumour resulting in higher drug accumulation. Enzyme-labile (peptide-based) linkers. The vc dipeptide linker, which is cleaved preferentially by the lysosomal protease, cathepsin B, ...
observed differences based on the conformation of the antigen, it is possible that CL variation effects may be antibody-antigen interaction dependent18 and cannot be generalized to all antibodies. It is likely that the structural and rigidity of the antibody, influenced by modification in the light...
In addition to that, the library generation process allows for combinatorial mixing of antibody genes that may result in combinations that are not present naturally. Therefore, comparative analysis with sera may not represent the same antibody binding patterns that are being presented in the phage ...
A critical stage in the induction of antibody responses is the interaction of antigen molecules with the surface receptors of immunocompetent cells which may result in either immunity, or immune tolerance. The differences between the pattern of antigen binding to B cells in immunity and tolerance ...
Investigation and molecular mimicry of the antigen involved in the interaction between the monoclonal antibody 5D10 and the human breast cancer cell line MCF-7. Vandevyver, Caroline,Canarelli, St茅phane,Bossen, Claudia,Fisch, Igor,Motmans, Kris,Raus, Jef,Freitag, Ruth. Biotechnology and ...