Antigen processing and presentation is the process by which protein antigen is ingested by an antigen-presenting cell (APC), partially digested into peptide fragments and then displayed on the surface of the APC associated with an antigen-presenting molecule such as MHC class I or MHC class II,...
Antigen processing and presentation refer to the processes that occur within a cell that result in fragmentation (proteolysis) of proteins, association of the fragments with MHC (Major Histocompatibility Complex) molecules, and expression of ...
John Wiley & Sons, Ltd.Developmental DynamicsAllen PM, Unanue ER: Antigen processing and presentation by macrophages. Am J Anat 1984;170:483–490.
Antigen processing and presentation Self-MHC Restriction: T cells can only recognize Ag when it is presented with a self-MHC molecule on the membrane of an antigen presenting cell (APC). Self-MHC restriction of TH cells A. Rosenthal & E. Shevach APC T Cell Self-MHC restriction of TC ...
chapter6 antigen processing and presentation to t lymphocytes 国家基金合作协议书 - 中国科学技术大学生命科学学院 中国科学技术大学简介 《中国科学技术大学》课件 中国科学技术大学生命科学教学科研综合楼工程电气设计 毕业论文 数据科学导论-中国科学技术大学 细胞转染暨活细胞工作站技术 - 中国科学技术大学生命科学学院...
This process — referred to as antigen processing and presentation — allows T cells to continuously assess the intracellular and extracellular milieu for signs of infection or abnormal cell growth. Although MHC class I molecules typically bind peptides derived from endogenous proteins and MHC class ...
上海交通大学医学院免疫学教研室 * 抗原加工提呈(Antigen Processing and Presentation) 张 勇 T cells do not recognize native antigens Y Y B Y Y Y Y Y Y Y B Y T Y T Proliferation and antibody production No proliferation Cross-linking of surface membrane Ig Y B Y B Y B Y B Y B Y ...
1Antigen Processing and Presentationustcwhm@ustc.edu.cn
The four major antigen processing and presentation pathways are exogenous, endogenous, cross-presentation and autophagic. Professional APCs engulf antigens and express MHC class II and costimulatory molecules either inducibly or constitutively. Mature DCs can activate nave, effector and memory Tc and Th ...
AntigenProcessingandPresentation Introduction •Traditionalview: –MHCclassIImoleculespresentpeptidesderivedfromexogenousproteinstoCD4+Tcells. –MHCclassImoleculespresentpeptidesderivedfromcytosolic(nuclear)ERandmitochondrialproteinstoCD8+Tcells. Introduction •Updatedview: –MHCclassIImoleculespresentpeptidesderived...