Antigen presentation for central tolerance induction For effective central T cell tolerance, developing thymocytes must encounter a diverse range of self-antigens presented by various thymic cells. Here, the authors describe how medullary thymic epithelial cells, dendritic cells and B cells are uniquely...
Subsequent epitope spreading depended on antigen presentation and was compartmentalized by major histocompatibility complex (MHC). B cells carrying two MHC haplotypes could bridge the MHC barrier between B cells that did not share MHC. Thus, B cells directly relay autoreactivity between two separate ...
Antigen presentation to B cells. Trends Immunol. 37, 844-854.Heesters, B.A.; van der Poel, C.E.; Das, A.; Carroll, M.C. Antigen presentation to B cells. Trends Immunol. 2016, 37, 844-854. [CrossRef] [PubMed]antigen presentation cells. This is directly related to my proposed ...
Related to Antigen-presenting cells:perforin,Dendritic cells an·ti·gen (ăn′tĭ-jən)alsoan·ti·gene(-jēn′) n. A molecule that is capable of binding to an antibody or to an antigen receptor on a T cell, especially one that induces an immune response. An antigen is usually a...
antigen-presenting cell (redirected fromAntigen presenting cells) antigen-presenting cell A cell, such as a macrophage, a B cell or a dendritic cell, that presents processed antigenic peptides andMHCclass II molecules to the T cell receptor on CD4 T cells. ...
2.11.1Antigen-presenting cells Antigen-presenting cells (APCs) derive their name from their ability to communicate their interactions with pathogens to T-lymphocytes in thelymph nodes, a process known as “antigen presentation”. These cells act as a link between innate and adaptive immunity by pha...
AntigenPresentingCells&AntigenPresentation 武汉大学基础医学院免疫系熊洁 主要内容： 1、掌握抗原提呈细胞的概念、种类。2、熟悉抗原的处理和提呈的过程及抗原提呈机制。3、了解与抗原提呈作用相关的免疫分子及其在抗原递呈中的作用。 第一节抗原提呈细胞 AntigenPresentingCells 在机体特异性免疫应答过程中，...
7 APC and antigen presentation 抗原呈递细胞和抗原呈递 Antigen-presentingCells(APC)andAntigenPresentation免疫学系 T细胞受体如何识别抗原?T细胞受体类似于结合于细胞膜上的抗体Fab段 •B细胞受体或抗体识别多肽、蛋白、核酸、碳水化合物、脂质和小分子化合物•T细胞受体仅识别线性抗原肽(shortlinearpeptides)T细胞受体...
1、Antigen presentation抗原递呈Antibody-MediatedImmune Responsenaive B cells+antigen+complementCell-MediatedImmune Responseantigen-presenting cellsnaive helper T cellseffectorhelper T cells+memoryhelper T cellsnaivecytotoxic T cellseffector cytotoxic T cells+memory cytotoxic cellsactivatedB cellseffector B 2、 ...
文稿10.上课定稿antigen presentation.pptx,Antigen presentation Antigen presentationDefinitionAntigen-presenting cellsAntigen processing and presentation Definition of antigen presentation The process by which certain cells in the body (antigen-presenting