Fungal isolates were grown on 100 mL of potato dextrose broth (PDB) in a 250 mL Erlenmeyer flask for 5–8 days at 28 ± 2 °C under 120 rpm agitation. Cell-free culture extracts were obtained by centrifugation at 5000 rpm for 10–12 min. Crude cell-free culture extracts were eval...
In particular VOCs (volatile organic compounds) of TML9 were tested in vitro for their anti-phytopathogenic activity. Ethyl acetate (EA) extract of cell-free culture components of Colletotrichum aenigma TML3 exhibited broad-spectrum antifungal activity against four species of Candida and the major ...
Enrichment culture techniques produced more than 1200 isolates of lactic acid bacteria (LAB) that were screened for antifungal activity against the indicator mould Aspergillus fumigatus. Approximately 10% of the LAB were active, but only 4% had medium or strong activity in an agar plate assay. The...
decipiens by silica gel chromatography and reversed-phase HPLC, and its structure was assigned by single-crystal X-ray diffraction analysis. The isolation process was guided by in vitro bioassays for antifungal antagonism toward other coprophilous fungi. 展开 ...
Iturin A was found to activate the Kv protein, stimulating K+efflux from cell. In vitro tests confirmed interaction between iturin A and Kv protein. This study highlights Kv as one of the precise targets of iturin A in its antifungal activity, offering a novel target for the development of ...
coli were found for Ag-TA-5, suggesting the highest antibacterial activity. Figure 8 (a) Antifungal and (b) antibacterial activities of the bio-adhesive nanocomposites. Full size image The antimicrobial activity of TA involves several actions such as hindered cell metabolism, increased permeability ...
Fungal infections have increased globally due to the increment of the size of population at risk for fungal infection, which is a consequence of the increased use of immunosuppressive drugs and invasive techniques for advanced life support and extended l
Liposomal amphotericin B, , and are currently used for systemic and severe . Patients with malignant diseases are treated with () for the recovery of granulocytes after chemotherapy or hematopoietic (HC) transplantation. Since they have a high incidence of , they inevitably receive antifungal drugs ...
Bossche - Elsevier Science Publishers , Sole distributors for the USA and Canada, Elsevier Science Pub. Co. 被引量: 16发表: 1986年 In vitro–in vivo antifungal evaluation and structure–activity relationships of 3H-1,2-dithiole-3-thione derivatives As part of our project devoted to the search...
Most such cells had the DNA content of cells in the G2 phase of the cell cycle, suggesting that the drug inhibited some cellular process involved in normal bud growth but did not affect DNA replication. Disruption of actin assembly was found in many cells treated for 2 to 3 h, as was ...