Human poisoning by antifreeze mixture has been known for many years and its formula, HOC H2-CH20H, occupies a position between ethyl alcohol and glycerol. Mostly it has been drunk by mistake, but sometimes it has been ingested as a substitute for alcohol (Ross, 1956). The minimum lethal ...
Ethylene glycol poisoning is treated by giving 4-methylpyrazole, an antidote which inhibits alcohol dehydrogenase. Household products, such as sink cleaners, dishwashing detergents, and toilet cleaners, are also common causes of poisonings in small animals. The majority of cleaning detergents are ...
Stage 2: This occurs 12-24 hours after a dog or cat has gotten into antifreeze, and signs of “alcohol” poisoning appear to resolve, when underlying severe internal damage is still occurring. Signs of drunkenness seem to improve, but signs of an elevated heart rate, increase breathing effort...
Learn about antifreeze and cats: what to do if your cat drank antifreeze, symptoms of antifreeze poisoning to watch for, treatment and prevention.
Stage 1: This occurs within 30 minutes to 12 hours, and looks similar to alcohol poisoning. Signs of incoordination, drooling, vomiting, seizures, and excessive thirst and urination may be seen. Stage 2: This occurs within 12-24 hours post-exposure, and clinical signs seen to “resolve”...
Methanol, ethanol, ethylene glycol, alcohol-water solution and isopropanol can be used as candidates for antifreeze [122,142,143]. Furthermore, ethylene glycol can be used as coolant for PEMFC and isopropanol is the solvent for preparing MEA catalyst [122]. Thus, the use of antifreeze method ...
Treatment consists of blocking the formation of toxic metabolites using inhibitors ofalcoholdehydrogenase, such as Antizol, and correction of metabolic abnormalities. In patients with high ethylene glycol or methanol concentrations (≥ 50 mg/dL), significant metabolic acidosis, orrenal failure, hemodialysis...
Further increasing the importance of early recognition and treatment in cases of exposure is the fact that the preferred treatment and antidote for ethylene glycol poisoning — a compound called Fomepizole (a.k.a. 4-MP or Antizol-Vet) — at the request of the manufacturer,FDA approval for this...
Its disadvantage is easy to ignite , alcohol boiling point is low, evaporation losses. After the evaporation of the alcohol , antifreeze composition changes , the freezing point increases. In the mountains, the plateau region moving car should not use alcohol - water, antifreeze , because of the...
the two heretofore known substances for the treatment of EG poisoning are poor candidates for use as preventatives of poisoning in mixtures with EG. The inventors have discovered that some substances which can be practically incorporated into EG-based heat transfer fluid concentrates can act as ADH...