interferons and interleukins) may have a role in MDD.30As those immune mediators modulate key functions such as sleep, appetite, cognition and temperature regulation, any alterations in those mediators can contribute indirectly to the pathogenesis of MDD, by disrupting vital functions.30That theory i...
interferons and interleukins) may have a role in MDD.30As those immune mediators modulate key functions such as sleep, appetite, cognition and temperature regulation, any alterations in those mediators can contribute indirectly to the pathogenesis of MDD, by disrupting vital functions.30That theory i...
ACTH, in turn, stimulates the adrenal glands to secrete CORT. Additionally, there is a negative feedback phenomenon in which the hypothalamus and pituitary gland are inhibited by the release of CORT, a glucocorticoid that is associated with mood, stress, anxiety, and cognitive effects[105], [...
Amino acid neurotransmitters can be divided into two types of excitatory amino acid and inhibitory amino acid; the former includes Glu and Asp, while GABA and Tau belong to the latter. Some of the studies, whether in rodent models of depression or in depressed patients, indicate that the incre...