interferons and interleukins) may have a role in MDD.30As those immune mediators modulate key functions such as sleep, appetite, cognition and temperature regulation, any alterations in those mediators can contribute indirectly to the pathogenesis of MDD, by disrupting vital functions.30That theory i...
Buck explained, with serotonin signaling the presence of food and octopamine signaling its absence or a state of starvation. C. elegans, for instance, usually only lays eggs when food is on hand. But serotonin stimulates egg laying in the absence of food,...
A tetracyclic antidepressant is a type of older antidepressant medication that belongs to the class of tricyclic and tetracyclic antidepressants. These medications were commonly used from the 1950s to the 1980s and have been associated with higher rates of seizure incidence in certain patient population...
This work can be summarized in 3 main concepts: the first is that leptin sensitivity can be modulated by this antidepressant in adulthood, even upon obesity. Second, BDNF plays an important role in mediating FLX action on energy homeostasis. BDNF positive action on energy output has recently eme...
The invention relates to the observation that the p38 mitogen-activated protein kinase pathway is an important regulator of biogenic amine transporter (BAT) function. By using modul
usually only lays eggs when food is on hand. But serotonin stimulates egg laying in the absence of food, while octopamine inhibits egg laying even when food is nearby. Another example of interplay between the two chemicals is that pharyngeal pumping, the mechanism by which worms ingest food, ...