The recent paper by Cameron et al 1 raises some underlying issues regarding antidepressant prescribing for older adults.The study indicated that 'all adult patients' were eligible to participate. However, the mean age was 48 years (SD = 18 years). This suggests that almost no participants were...
Antidepressant Use Among Older Adults in British ColumbiaImpact, TheSharing, CostUse, AntidepressantOlder, AmongColumbia, British
This treatment would seem perfectly suited for older patients, given that they often suffer from various comorbidities and are typically taking several other medications that may complicate the use of regular antidepressants. However, since the early 2000s, it has been widely believed that rTMS is n...
Association of anxiety and depression with microtubule-associated protein 2- and synaptopodin-immunolabeled dendrite and spine densities in hippocampal CA3 of older humans. Arch Gen Psychiatry. 2010;67:448–57. Article PubMed PubMed Central Google Scholar Bora E, Fornito A, Pantelis C, Yücel M...
Side effects may contribute to abrupt discontinuation of antidepressants, and the abrupt discontinuation of SSRIs is associated with discontinuation syndrome, in selecting antidepressants for the older adults, clinicians must consider age of patients, pharmacodynamics and pharmacokinetics of antidepressants, ...
A tune in "a minor" can "b major": a review of epidemiology, illness course, and public health implications of subthreshold depression in older adults. J Affect Disord. 2011;129(1-3):126–42. 6. Koenig AM, Bhalla RK, Butters MA. Cognitive functioning and late-life depression. J Int ...
IMPORTANCE: More than 50% of older adults with late-life major depressive disorder fail to respond to initial treatment with first-line pharmacological therapy. OBJECTIVES: To assess typical patterns of response to an open-label trial of extended-release venlafaxine hydrochloride (venlafaxine XR) for...
Our intended audience is the generalist, who may be called on to treat older adolescents for whom the demarcation between adulthood and adolescence may not be clear-cut. From the vantage point of the clinical psychopharmacologist who treats adults, several areas require special attention in ...
for up to 12 weeks: women were about 1.5× as likely to achieve remission as men, with most patients in the study taking either SSRIs or SNRIs [159]. In conjunction with findings that older women do not enjoy this superiority and that hormone replacement therapy has been found to ...
Antidepressant Therapy in Older Adults: A Network Meta-Analysis In a recent meta-analysis of randomized, placebo-controlled trials, researchers found antidepressant drugs — analyzed collectively — to be only A Brett - 《Nejm Journal Watch》 被引量: 0发表: 2015年 Psychotherapy versus the ...