refrigeration- deliberately lowering the body's temperature for therapeutic purposes; "refrigeration by immersing the patient's body in a cold bath" thermotherapy- the use of heat to treat a disease or disorder; heating pads or hot compresses or hot-water bottles are used to promote circulation ...
heparin,Lipo-Hepin,Liquaemin- a polysaccharide produced in basophils (especially in the lung and liver) and that inhibits the activity of thrombin in coagulation of the blood; it (trade names Lipo-Hepin and Liquaemin) is used as an anticoagulant in the treatment of thrombosis and in heart ...
which introduces micro-embolic bubbles and shear stress11, leading to hemolysis and a decrease in the number of collected red blood cells (RBCs), and compromised blood quality12. Without anticoagulation, the extracorporeal
Recently, advanced drug delivery systems such as using either functional nanoparticles or endogenous albumin have gained attention for increasing the action time of drugs in the body during therapy17,18. Despite the attempts to develop nano-sized, long-acting heparins19,20, encapsulating heparin molec...
Variability of the anticoagulant effect according to body weight in patients treated with direct oral anticoagulantsdoi:10.1007/s11739-024-03553-3Belli, LorenzoRadico, FrancescoAuciello, RaffaellaPatti, GiuseppeGallina, SabinaRenda, GiuliaSpringer International PublishingInternal & Emergency Medicine...
A body weight below <50–60 kg in healthy volunteers or patients with AF seems to result in up to 27 % higher apixaban [17,18] and 40 % higher edoxaban plasma levels [19,20], while the impact on rivaroxaban and dabigatran levels appears clinically negligible [[21], [22], [23], [...
(AF) or venous thromboembolism (VTE) and are often treatedwith antithrombotic drugs.1 Direct oral anticoagulants (DOACs) have replaced vitamin K antagonists for many indications, but clinicians avoid DOACs in patients with high body weight because of concerns that decreased drug exposure will reduce ...
To attain this by anticoagulants, the physician must recognize that he is thereby tampering with one of the most important and complicated homeostatic mechanisms of the body. Despite notable recent advances in this area, many vexatious problems continue to beset the physician. First, let us examine...
Lupus anticoagulants cause clotting disorders that can lead togangrene, miscarriages, strokes, and other problems. The lupus anticoagulant test measures the level of those antibodies in your body. Lupus Anticoagulant Test The lupus anticoagulant test is a blood test that checks for antibodies that caus...
body weight at the time ofcannulation, and then UNFH is continuously infused during ECMO. The dose is usually of 7.5 to 20 units/kg/hr, lower in the adults and higher forpediatricand neonatal patients. Therapeuticanticoagulation, classically defined byACTrange of 180 to 220 seconds, typically ...