Anticoagulant, any drug that, when added to blood, prevents it from clotting. Anticoagulants achieve their effect by suppressing the synthesis or function of various clotting factors that are normally present in the blood. Such drugs are often used to pr
Variability of the anticoagulant effect according to body weight in patients treated with direct oral anticoagulantsdoi:10.1007/s11739-024-03553-3Belli, LorenzoRadico, FrancescoAuciello, RaffaellaPatti, GiuseppeGallina, SabinaRenda, GiuliaSpringer International PublishingInternal & Emergency Medicine...
providing the necessary electrical energy for heart rate sensors after implantation, but also effectively prevents the activation of the blood coagulation pathway, and the occurrence of adverse clinical reactions such as platelet adhesion, thrombosis, and inflammation when implanted in the body or in dir...
a我在你的心是什么位置? What position am I in yours heart?[translate] a我们的施工管理将工期管理、质量管理、成本管理、安全管理为一体。 Our construct control the time limit for a project management, the quality control, the cost management, the safety control is a body.[translate] ...
A body weight below <50–60 kg in healthy volunteers or patients with AF seems to result in up to 27 % higher apixaban [17,18] and 40 % higher edoxaban plasma levels [19,20], while the impact on rivaroxaban and dabigatran levels appears clinically negligible [[21], [22], [23], [...
particularly anticoagulant activity. This addresses the issue of implantable energy storage devices lacking a thrombus protection mechanism in the body, which can result in blood coagulation, thrombus, and other threats to human health and affect the normal operation of the device. It provides a solut...
Recently, advanced drug delivery systems such as using either functional nanoparticles or endogenous albumin have gained attention for increasing the action time of drugs in the body during therapy17,18. Despite the attempts to develop nano-sized, long-acting heparins19,20, encapsulating heparin molec...
Objective: To study the anticoagulant constituents in dried leech(Whitmania pigra Whitman).Method: The plasma recalcification time(PRT) as index,the constituents with anticoagulant activity were isolated and purified by anion-exchange chromatography on Sephadex DEAE A-50,gel permeation chromatography on ...
In clinical trials, adherence to a prescribed regimen with dabigatran was enhanced by frequent follow-up visits and pill counts.ObjectivesTo describe the experience of dabigatran treatment in clinical practice, focusing on adherence.Patients/methodsIn a cross-sectional cohort study, we interviewed 103 ...
The coumarins and indanediones are synthetic compounds which are effective after oral dosage. Unlike heparin they have no effect on clotting if added to whole bloodin vitro.They act indirectly, that is they must be absorbed and metabolized by the body before they produce an effect. It is known...