1916, mclean from the dog liver in the study of blood clotting problems found this anti-clotting substances, and the name of heparin. 翻译结果2复制译文编辑译文朗读译文返回顶部 翻译结果3复制译文编辑译文朗读译文返回顶部 In 1916, Mclean from dogs in the study on blood coagulation problems this an...
The onset of action of oral anticoagulants is delayed, even if they are given i.v. Anticoagulation coincides with the appearance of defective clotting factors in the blood and the disappearance of normal factors. Because this requires hours, a heparin-based anticoagulant is used to produce an ...
Vascular dysfunction resulting in deficiency of blood supply into the brain is one of the principal mechanisms of Vascular Dementia (VaD).The pathogenesis of VaD is related to a thrombotic process with two distinct mechanismsmultiple micro-infarcts1, associated with a single symptomatic infarct; so ...
The development of a circulating anticoagulant is thought to occur in 10 to 15% of patients with systemic lupus erythematosus (SLE) at some time during the course of their illness. With notable exceptions, the presence of so-called lupus anticoagulant is not associated with hemorrhagic episodes, ...
The observed effect is the first indication that dipeptide can cause an increase in the blood clotting time in vivo. It should be noted that the tryptophan-containing dipeptides, including IleTrp and LeuTrp, which have been found in food protein hydrolysates, are inhibitors of angiotensin ...
The term lupusanticoagulantsis an inaccurate term. It was first coined when blood samples from lupus patients were tested and didn’t clot within a specific amount of time. But while lupus patients can have these antibodies, they aren’t only found in lupus and they aren’t only associated ...
The latter demonstrates the blood anticoagulant property by antagonism of vitamin K and acted as a forerunner of the synthetic anticoagulants typified by warfarin3. Warfarin is one of the most prescribed oral anticoagulants worldwide and had a global market value of $300 million in 2008 (ref. 4...
Michael J.Day, inSystemic Lupus Erythematosus (Fifth Edition), 2011 Lupus anticoagulant Thelupus anticoagulanthas been investigated in dogs with autoimmune hemolytic anemia with secondary pulmonary thromboembolism[66]. However, this antibody is rarely found and such patients also lack autoantibodies reactive...
designated as anticoagulant HS. On the basis of heparin's pharmacological mechanism of action, it has long been proposed that,in vivo, endothelial HSAT+would activate AT and thereby regulate antithrombotic tone of theblood vessel wall. The objective of this chapter is to evaluate whether the ...
30.The method of claim 29, wherein said condition is a member selected from the group consisting of deep venous thrombosis, blood clots, pulmonary embolism, unstable angina, atrial fibrillation, acute myocardial infarction, coronary angioplasty, stent placement, coronary artery bypass graft, pulmonary...