例句>> 5) targeting drug carrier 靶向药物载体 1. A new magnetic targeting drug carrier material (MTDCM) was prepared by complex magnetic nano-particles using purified attapulgite as raw material. 以提纯凹凸棒石矿物为原料,通过纳米磁性粒子复合,制备成新型矿物磁性靶向药物载体材料。 更多例句>> 6...
1)Antibody-based drug抗体靶向药物 英文短句/例句 1.Study on Antibody Targeting Drug Constructed by Coupled Serum Antibody Against E.coli and Gentamicin Sulfate;大肠杆菌血清抗体与硫酸庆大霉素偶联构建抗体靶向药物的研究 2.Antibody-drug conjugates as targeted cancer therapeutics靶向癌症治疗试剂——抗体-药物...
Moreover, both of an antibody fragment and a LPT can be integrated into the molecule of conjugate or fusion protein, resulting in a drug with bi-specific activity. tZhen YongsuProceedings of international symposium on crystal engineering and drug delivery system 2009: International symposium on ...
4) anti-drug monoclonal antibodies 药物单克隆抗体 1. The methods and principles for the preparation of drug-protein conjugates as immunogen and the main points of producing anti-drug monoclonal antibodies with B-lymphoblasts hybridoma technique are introduced briefly in this paper. 概述了药物(含...
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The development of antibody-drug conjugates (ADCs) takes advantage of the specificity of the monoclonal antibody and potent cytotoxic effect of chemotherapy, leading to enhanced cytotoxicity in target cells and limiting toxicity to normal tissue. Microtubules represent a validated oncologic target in a ...
Since the successful approval of gemtuzumab ozogamicin, antibody-drug conjugates (ADCs) have emerged as a pivotal category of targeted therapies for cancer. Among these ADCs, the use of monomethyl auristatin E (MMAE) as a payload is prevalent in the development of ADC drugs, which has significant...
Target selection for antibody-drug conjugates (ADCs) frequently focuses on identifying antigens with differential expression in tumor and normal tissue, to mitigate the risk of on-target toxicity. However, this strategy restricts the possible target space. SLC34A2/NaPi2b is a sodium phosphate transpo...
U. Current trends in the clinical development of antibody–drug conjugates in oncology. Pharmaceut. Med. 32, 259–273 (2018). CAS Google Scholar Hartley, J. A. et al. Pre-clinical pharmacology and mechanism of action of SG3199, the pyrrolobenzodiazepine (PBD) dimer warhead component of ...
Flygare et al., Antibody-Drug Conjugates for the Treatment of Cancer, Chem. Biol. Drug Des., 2013, Issue 1, pp. 113-121, vol. 81. Gomathinayagam et al., High-Throughput Multimodal Strong Anion Exchange Puri fi cation and N-Glycan Characterization of Endogenous Glycoprotein Expressed in ...