HUMAN ANTIBODY AND FRAGMENTS THEREOF FOR USE IN THE TREATMENT OF GASTRIC CANCER (GC) AND OTHER TYPES OF TUMOURS EXPRESSING THE MICA PROTEIN (MHC CLASS I CHAIN-RELATED PROTEIN A GENE) A bivalent, anti-MICA human monoclonal antibody formed by two or more heavy and light chains with a variable...
Melioidosis, caused by Burkholderia pseudomallei (Bpm), lacks a vaccine. We identify the immune correlates of protection induced by B. mallei ΔtonB Δhcp1 (CLH001) and Bpm ΔtonB Δhcp1 (PBK001) vaccines against inhalational melioidosis. Mucosal immuniz
The effect of placental transport on the function of IgG anti- bodies has not been examined extensively. Hemming et al. (33) found that maternal IgG opsonins for three types of group B streptococci crossed the placenta and appeared in paired cord specimens from most infants. However, most ...
Although some evidence suggests variation in tissue types and developing embryos (PMID: 23099774) if expression is stable across conditions, beta-actin is still considered by many to be a suitable gene for normalization. Beyond its role as a housekeeping gene, it has been shown that beta-actin ...
Function and Structure 2.2. Basic Structure 2.3. Heavy Chains 2.4. Light Chains 2.5. Variable and Constant Regions 2.6. Three-Dimensional Structure 2.7. Fragments 2.8. Carbohydrates 2.9. Structural Features of the Immunoglobulin Classes View chapterExplore book Computational and artificial intelligence-base...
Tumor progression in vivo was evaluated in various types of tumorigenesis models including C57BL/6 mice, Balb/c mice, and SCID mice. The phenotype and function of immune cells in tumor microenvironment were characterized with multi-color flow cytometry. Tumor stemness was detected by ALDH assays....
We use essential cookies to make sure the site can function. We also use optional cookies for advertising, personalisation of content, usage analysis, and social media. By accepting optional cookies, you consent to the processing of your personal data - including transfers to third parties. Some...
(autoTresh = T) function was 0.82. For the pool of 3 SARS-CoV-2 patients, it was 0.84. (Fig.1). Cell clustering analysis demonstrated a presence of all major cell types (T/NK cells, B cells, DCs/monocytes etc.) across 3 individuals in both pools, with no big variation of hashing...
and function John E Bradley1, Joy M Chan2 and James S Hagood3 Thymocyte differentiation antigen-1 (Thy-1) is a glycosylphosphatidylinositol (GPI)-linked cell surface glycoprotein expressed on numerous cell types, which regulates signals affecting cell adhesion, migration, differentiation, and ...
We use essential cookies to make sure the site can function. We also use optional cookies for advertising, personalisation of content, usage analysis, and social media. By accepting optional cookies, you consent to the processing of your personal data - including transfers to third parties. Some...