Antibody-dependent enhancement of dengue virus infection in primary human macrophages; balancing higher fusion against antiviral responses. Sci Rep. 2016; 6: 29201.Flipse J, Mayra A. Diosa-Toro, Tabitha E. Hoornweg, Denise P. I. van de Pol, Silvio Urcuqui-Inchima, Jolanda M. Smit. ...
16. Antibody-dependent enhancement of infection (ADE) that increases the viremia level has been proposed as one of the pathogenic mechanisms in DHF/DSS17; in the case of ADE the increase occurs by viral internalization via Fc gamma receptors18. Recently, a potential relationship between ADE...
Oral medications that are particularly dependent on threshold concentrations for efficacy, such as antibiotics, or medications for which a delay in effect is undesirable, such as acetaminophen, should be administered 1 hour before ADLYXIN…[o]ral contraceptives should be taken at least 1 hour before...
Margetuximab is an anti-HER2 antibody that binds with elevated affinity to both the lower and higher affinity forms of CD16A, an Fc-receptor important for antibody dependent cell-mediated cytotoxicity (ADCC) against tumor cells. A Phase 1 study was initiated to evaluate the toxicity profile, ma...
Print datasheet MSDS ¥2200/100 μL Cat No.18985-1-AP 浓度:1200 ug/ml 库存:现货 Size 点击咨询在线客服 humanWB See more citations
Cat No.17590-1-AP 浓度:600 ug/ml 库存:现货 Size 点击咨询在线客服 mouseWB View Article WB Small M2 Macrophage Membrane-Mediated Biomimetic-Nanoparticle Carrying COX-siRNA Targeted Delivery for Prevention of Tendon Adhesions by Inhibiting Inflammation ...
The enhancements in phagocytosis described here provide the potential to improve the performance of therapeutic antibodies targeting cancers. 展开 关键词: Humans Macrophages Cell Line Antibodies Binding Sites, Antibody Antibody-Dependent Cell Cytotoxicity Receptors, IgG Phagocytosis ...
This approach to finding antibodies has advantages over a Google search, which is dependent on many factors which do not directly relate to antibody quality. For example, the supplier with the best search engine optimisation does not necessarily provide the most suitable antibody. There are existing...
Those transitions are either the concentration-dependent addition or the subtraction of a single antibody to the system via monovalent binding or unbinding: $${\sigma }_{i}\mathop{\rightleftharpoons}\limits^{{{c}_{\mathrm{Ab}}{k}_{1}}}_{{{k}_{-1}}}{\sigma }_{j},$$ (69) ...
Once the FcR is engaged by the Fc domain, the FcR may initiate functions including, for example, clearance of an antigen-antibody complex via receptor-mediated endocytosis, antibody-dependent cell-mediated cytotoxicity (ADCC), antibody dependent cell-mediated phagocytosis (ADCP), trogocytosis, trogo...