Antibody-antigen interactionInvariant point attentionAntibody structure predictionAntibodies play a crucial role in disease treatment, leveraging their ability to selectively interact with the specific antigen. However, screening antibody gene sequences for target antigens via biological experiments is extremely...
Traditional protein–protein interaction prediction methods often fall short because they do not account for the unique structural and dynamic properties of antibodies and antigens. In this study, we present AntiBinder, a novel predictive model specifically designed to address these challenges. Anti...
Prediction of antibody-antigen interaction based on backbone aware with invariant point attention Antibodies play a crucial role in disease treatment, leveraging their ability to selectively interact with the specific antigen. However, screening antibod... M Gu,W Yang,M Liu - 《Bmc Bioinformatics》 ...
3.1. Antigen-Antibody Interaction Most antigen-antibody complexes have the characteristics of other well-studied protein-protein interactions. The free energy of binding is a function of the amount of surface of each protein (antigen and antibody) which is hidden within the complex from exposure to...
Machine learning (ML) is a key technology for accurate prediction of antibody–antigen binding. Two orthogonal problems hinder the application of ML to antibody-specificity prediction and the benchmarking thereof: the lack of a unified ML formalization of immunological antibody-specificity prediction prob...
Consider first the simple 1–1 interaction of an antibody analyte that binds and unbinds to a structure containing a single antigen ligand. $${\sigma}_{\_}\mathop{\rightleftharpoons }\limits_{{k}_{-1}}^{{c}_{\mathrm{Ab}}{k}_{1}}{\sigma }_{\mathrm{Ab}},$$ (5) where σ...
Antigen-antibody interaction on microcapsule surface 来自 Semantic Scholar 喜欢 0 阅读量: 30 作者:K Makino,M Arakawa,T Kondo 摘要: An introductory review is given to the study of two-dimensional phase transitions, as most easily observed on lamellar solids. Two examples have been chosen, namely...
Methods for the study of antigen-antibody interaction. Thermodynamic aspects of antigen-antibody interaction. Type of bonds which intervene in the interaction of the antibody with the antigen. Antigen-antibody reaction - reversible reaction. Equilibrium constant. Affinity. Determination of affinity. Specifi...
Deep learning models for antibody structure prediction present several promising avenues toward antibody design. In this work, we demonstrated how our network could be used to suggest or screen point mutations. Even with no explicit knowledge of the antigen, this approach was already moderately predict...
网络抗体交互作用;抗原抗体反应;抗体反应 网络释义