Pretrainable geometric graph neural network for antibody affinity maturation Increasing the binding affinity of an antibody to its target antigen is key for antibody therapeutics. Here the authors report a pretrainable geometric graph neural network, GearBind, and explore its potential in in silico ...
Differences in the observed Ig functionality can be explained by the differences in binding affinity to elements of the complement pathway as well as binding affinity to Fc gamma receptors expressed on immune cells that drive the ADCC/ADCP responses. IgGs owe their unusually long half-lif...
Affinity chromatography 保存液 PBS, pH 7.2, with 0.2% BSA 内含物 0.09% sodium azide 保存条件 4° C, store in dark, DO NOT FREEZE! 运输条件 Ambient (domestic); Wet ice (international) RRID AB_11039758 产品详细信息 Description: The eB-h209 monoclonal antibody reacts with huma...
Affinity chromatography 保存液 PBS, pH 7.2 内含物 0.09% sodium azide 保存条件 4° C, store in dark, DO NOT FREEZE! 运输条件 Ambient (domestic); Wet ice (international) RRID AB_10598664 产品详细信息 Description: The monoclonal antibody 29A1.4 recognizes mouse NKp46, also known...
More recently, coarse-grained molecular simulations have been fruitfully used to quantify the effects of the cooperative binding of the antibody subunits on binding affinity16,17. Nevertheless, a challenge of precisely calibrating such models remains due to the absence of experimental tools to ...
Purification:affinity purified by Protein A Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Background:This gene encodes a subunit of interleukin 12, a cytokine that acts on T ...
the HEL mutant binds to HyHEL-5 with a 103-fold reduction in affinity. The crystal structure demonstrated that lysine is unable to form both salt bridges to a HyHEL-5 glutamate, therefore the decrease in affinity of the HyHEL-5 reaction with the mutant HEL was ascribed to the loss of ...
Purification Method Antigen affinity purification Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Storage Conditions Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. Background Information Arginase-...
Purification MethodAntigen affinity purification Storage BufferPBS with 0.02% sodium azide and 50% glycerol pH 7.3. Storage ConditionsStore at -20°C. Stable for one year after shipment.Aliquoting is unnecessary for -20oC storage.20ul sizes contain 0.1% BSA. ...
Affinity chromatography 保存液 PBS, pH 7.2 内含物 0.09% sodium azide 保存条件 4° C, store in dark, DO NOT FREEZE! 运输条件 Ambient (domestic); Wet ice (international) RRID AB_465439 产品详细信息 Description: The 6C2 monoclonal antibody reacts with mouse Toll-like receptor 2 (TLR2). mous...